Example sentences for: perinatal

How can you use “perinatal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Monochorionic pregnancies have an approximately 15% risk of developing the twin-to-twin transfusion syndrome (TTTS), which can be associated with perinatal mortality and morbidity despite treatment [5].

  • Yet, elevated maternal mid-trimester chorionic gonadotropin is associated with fetal cerebral blood flow redistribution and adverse perinatal outcome [ 63 ] . In addition, estrogens, which are known to cause a diminution of high LH levels in postmenopausal women, have been reported to be effective in the prevention and treatment of Alzheimer's disease [ 72 73 74 ] . Microglia belong among cells of the mononuclear phagocyte system [ 75 ] . Since CG increases secretion of a variety of cytokines by monocytes, and induces their inflammatory reaction and phagocytic activity [ 76 77 78 79 ] , high LH levels in aging individuals may also activate resident macrophages in the central nervous system and contribute to the development of Alzheimer's disease and other inflammation-mediated neurodegenerative diseases.

  • This resembles high LHR expression in first trimester placenta [ 28 ] , which is a source of high hCG levels [ 59 ] . Yet, hCG levels fall during the second trimester, and elevated maternal midtrimester hCG is associated with higher rates of maternal and neonatal complications (pregnancy-induced hypertension, preeclampsia, gestational diabetes, and perinatal death) [ 60 61 62 63 ] .

  • Thus, BMPs 6, 7, and 60A stimulate dendritic growth in cultured sympathetic neurons derived from either perinatal or adult ganglia in the absence of effects on cell survival or axonal growth [ 15 16 17 ] . BMP-7 has also been shown to enhance dendritic growth in hippocampal, cortical and spinal motor neurons [ 18 19 20 ] .

  • For example, zidovudine was found to prevent a large fraction of perinatal HIV infections [23], even though studies in animal models, conducted with high challenge doses, could not establish any protection against infection by zidovudine [20–22].


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