Example sentences for: perinatal

How can you use “perinatal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The link between monochorionicity and adverse perinatal outcomes has become increasingly strong [4].

  • This resembles high LHR expression in first trimester placenta [ 28 ] , which is a source of high hCG levels [ 59 ] . Yet, hCG levels fall during the second trimester, and elevated maternal midtrimester hCG is associated with higher rates of maternal and neonatal complications (pregnancy-induced hypertension, preeclampsia, gestational diabetes, and perinatal death) [ 60 61 62 63 ] .

  • NTDs are second only to congenital heart defects as a cause of perinatal mortality due to birth defect and range in incidence from 0.5 to 12 per 1000 live births, depending on the country, accounting for 400,000 births world-wide annually.

  • Yet, elevated maternal mid-trimester chorionic gonadotropin is associated with fetal cerebral blood flow redistribution and adverse perinatal outcome [ 63 ] . In addition, estrogens, which are known to cause a diminution of high LH levels in postmenopausal women, have been reported to be effective in the prevention and treatment of Alzheimer's disease [ 72 73 74 ] . Microglia belong among cells of the mononuclear phagocyte system [ 75 ] . Since CG increases secretion of a variety of cytokines by monocytes, and induces their inflammatory reaction and phagocytic activity [ 76 77 78 79 ] , high LH levels in aging individuals may also activate resident macrophages in the central nervous system and contribute to the development of Alzheimer's disease and other inflammation-mediated neurodegenerative diseases.

  • For example, zidovudine was found to prevent a large fraction of perinatal HIV infections [23], even though studies in animal models, conducted with high challenge doses, could not establish any protection against infection by zidovudine [20–22].


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