Example sentences for: perforin

How can you use “perforin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Previously, such systematic differences in the two technologies were reported [ 6 ] . For example, perforin showed a 103-fold change in the Affymetrix array, whereas the cDNA microarray showed only a balanced differential expression of 3.8-fold.

  • The blot demonstrated the up-regulation of the perforin transcript in leukemia LGL cells (Fig.

  • The two latter effector memory populations contain perforin, secrete IFN-γ and tumor necrosis factor-α, are cytotoxic, and are capable of rapid effector function after stimulation [ 9 10 11 ] .

  • Inflammation and production of chemokines such as macrophage inflammatory protein-1α and RANTES [ 7 8 ] in the synovium may result in preferential recruitment of such effector memory CD8 +T cells (which are important contributors to IFN-γ production) and subsequent macrophage activation, because terminally differentiated CD45RA +CD62L -CD8 +T cells have been shown to express higher levels of perforin and may be more potent effector cells [ 10 ] . The question arises of whether the observed skewed differentiation of CD8 +T cells in RA patients is due to medication, especially steroids.

  • For example, perforin transcripts showed strong hybridization to both PM and MM probe sets.


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