Words similar to perfect-match
Example sentences for: perfect-match
How can you use “perfect-match” in a sentence? Here are some example sentences to help you improve your vocabulary:
There are two common experimental platforms for expression profiling; redundant oligonucleotide arrays (Affymetrix GeneChips) [ 1 ] , and spotted cDNA microarrays [ 2 3 4 ] . The Affymetrix GeneChips have the inherent advantages of redundancy, specificity, and transportability; there are typically 30-40 oligonucleotide probes (features) designed against each gene tested by the array, with paired perfect-match and mismatch probes, with standardized factory synthesis of arrays [ 5 6 ] . The uniform nature of the arrays permits databasing of individual profiles, which facilitates comparison of data generated by different laboratories.
The resulting hybridization intensity measurements for each oligonucleotide were averaged across all hybridizations and scaled as a fraction of the average intensity of the perfect-match oligonucleotide for each set.
Each pair consists of a 'perfect-match' primer and a 'mismatch' primer that has a single base change from the perfect match and is meant to control for nonspecific hybridization effects.
For each gene (probe set), the Affymetrix software calculates an 'average difference' between the intensities of the perfect-match and mismatch primers, and additionally makes an overall determination as to the absence or presence of a gene (absent/present call) in the sample.
The absolute signal distributions of the six oligonucleotide arrays can be seen in Figure 2for the HIV (perfect-match (PM) distributions) and glnA (Cy3 G and Cy5 R distributions) experiments both before and after normalization.
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