Words similar to peptide-specific
Example sentences for: peptide-specific
How can you use “peptide-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:
To quantify insulin expression in IPCs, we used a human insulin C-peptide-specific ELISA (see Figure 4P).
Therefore, optimized use of heteroclitic peptide to induce an initial peptide-specific T cell response, followed by selective expansion of the highest RE tumor-lytic T cells may be needed for an effective strategy with clear clinical application.
In recent cancer vaccine trials [3,4,5], many melanoma patients who received heteroclitic peptide vaccines gp100 209–217 (210M) (IMDQVPSFV; G209–2M) and MART 26–35 (27L) (ELAGIGILTV; M26) had measurable CD8+ peptide-specific T cell responses in PBMCs detected by peptide–MHC tetramer staining.
For isolation and detection of peptide-specific T cells, patient PBMC samples were stained and analyzed by fluorescence-activated cell sorting (FACS) as previously described [2].
In our system, we cannot distinguish if the amino acid change we have created has its effects on binding to the guinea pig MHC, interaction with the T cell receptor, or more efficient processing of the epitope from the protein precursor [ 51 ] . Any or all of these mechanisms could contribute to the enrichment for peptide-specific proliferative responses seen in vitro.