Words similar to peptide-specific
Example sentences for: peptide-specific
How can you use “peptide-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:
To quantify insulin expression in IPCs, we used a human insulin C-peptide-specific ELISA (see Figure 4P).
For isolation and detection of peptide-specific T cells, patient PBMC samples were stained and analyzed by fluorescence-activated cell sorting (FACS) as previously described [2].
In recent cancer vaccine trials [3,4,5], many melanoma patients who received heteroclitic peptide vaccines gp100 209–217 (210M) (IMDQVPSFV; G209–2M) and MART 26–35 (27L) (ELAGIGILTV; M26) had measurable CD8+ peptide-specific T cell responses in PBMCs detected by peptide–MHC tetramer staining.
Therefore, optimized use of heteroclitic peptide to induce an initial peptide-specific T cell response, followed by selective expansion of the highest RE tumor-lytic T cells may be needed for an effective strategy with clear clinical application.
In our system, we cannot distinguish if the amino acid change we have created has its effects on binding to the guinea pig MHC, interaction with the T cell receptor, or more efficient processing of the epitope from the protein precursor [ 51 ] . Any or all of these mechanisms could contribute to the enrichment for peptide-specific proliferative responses seen in vitro.
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