Example sentences for: penicillins

How can you use “penicillins” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • L1's preference for penicillins and carbapenems over cephalosporins, as exemplified by the k cat values, is in agreement with previous studies and supports L1's placement in the β-lactamase 3c family [ 9 ] .

  • On the other hand, the K m and k cat values for the I164A mutant when the penicillins or carbapenems were used as substrates were very similar to those numbers exhibited by wild-type L1 (Tables 4and 5).

  • Beta-lactamases have been widely investigated for their role in the metabolism of antibiotics including cephalosporins and penicillins.

  • Only when Ser224 was replaced with an Asp residue was there significant increases in the observed K m value for 6 of the 9 substrates tested, and the largest changes were exhibited when the penicillins were used as substrates.

  • These bacteria become resistant by a number of mechanisms, such as producing enzymes that hydrolyze or inactivate the antibiotics, producing efflux pumps that transport the antibiotic out of the cell, or modifying their cell wall components so they no longer bind effectively to the antibiotics [ 1 2 3 ] . The most common, least expensive, and effective antibiotics are the β-lactam containing antibiotics, such as the penicillins, cephalosporins, and carbapenems [ 2 4 5 ] . These antibiotics are mechanism-based inhibitors of transpeptidase, a bacterial enzyme required for the production of a strong viable cell wall [ 6 7 ] . In response to the widespread use of β-lactam containing antibiotics, bacteria have acquired the ability to produce β-lactamases, which are enzymes that hydrolyze and inactivate β-lactam containing antibiotics.


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