Words similar to penicillins
Example sentences for: penicillins
How can you use “penicillins” in a sentence? Here are some example sentences to help you improve your vocabulary:
Only when Ser224 was replaced with an Asp residue was there significant increases in the observed K m value for 6 of the 9 substrates tested, and the largest changes were exhibited when the penicillins were used as substrates.
As a first approximation of substrate binding, we examined the steady-state kinetics of 4 cephalosporins, 2 penicillins, and 3 carbapenems (Tables 3, 4, 5) and compared the K m values of the mutants with those of wild-type L1.
Generally, the S224A and S224K mutants exhibited small changes in K m and k cat , while the S224D mutant yielded 20- to 40-fold increased values for K m and >10-fold decreases in k cat when using the penicillins as substrates.
Two penicillins were tested as substrates, and penicillin G and ampicillin exhibited K m values of 38 ± 12 μM and 55 ± 5 μM and k cat values of 600 ± 100 s -1and 520 ± 10 s -1, respectively (Table 4).
When penicillins were used as substrates, the Tyr228 mutants exhibited 3- to 13-fold increased K m values and < 2-fold changes in k cat , as compared to the values ascertained using wild-type L1 (Table 4).
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