Words similar to penetrance

Example sentences for: penetrance

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This includes the L72 locus, which has a reduced penetrance of cosuppression that may be attributable to its pericentromeric location [ 27 ] . Intriguingly, both trans-silencer loci, C73 and C97, belong to the 'complex' group, adding weight to the proposition that, like paramutagenicity, trans-silencing activity is encoded epigenetically.
These include: low sibling relative risks due to the high population prevalence; presence of multiple genetic loci, each contributing a small portion of the sibling relative risk; incomplete penetrance of genetic loci; environmental risk factors; late age at onset; and phenocopies, i.e. disease due to purely environmental factors.
Assuming autosomal dominant inheritance with complete penetrance, two families (AG, E) are not linked and five families are inconsistent with linkage (AJ, AH, T, CT, BT) to the FEOM2 locus (see Additional File 3).
For this model, the high-risk genotypecombinations are AAbb , AaBb , and aaBB withdisease penetrance of 0.1, 0.05, and 0.1 respectively.
By 6 months of age, heterozygous mice develop tumors of the lymphoid system, colon, uterus, and adrenal medulla with very high penetrance, and tumors of the prostate and thyroid with lower penetrance.