Example sentences for: pellucida

How can you use “pellucida” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These mice also develop autoimmunity against thyroid and gastric parietal cells [ 22 ] . It is well established that these mice with ovarian autoimmunity also develop circulating autoantibodies against the oocyte cytoplasm, the zona pellucida, and against steroid producing cells [ 22 ] . While we found evidence that one half of our patients had specific antibodies directed against the zona pellucida, we did not find any consistent pattern of immunofluorescence to suggest that our patients had antibodies directed against the oocyte cytoplasm or the steroid producing cells of the ovary.

  • Also, this finding suggests that the detection system is specific for zona pellucida, and that further refinement of the assay system by using pure human recombinant zona pellucida protein might be useful.

  • There is now compelling evidence demonstrating that CD9, a tetraspan membrane protein, is present on the oolemma and essential for sperm-egg fusion, possibly by organizing functional multimolecular complexes in the egg [ 7 ] . Glycosyl-phophatidyniositol (GPI)-anchored proteins have also been described on the oolemma and implicated in sperm-egg fusion; removal of GPI-anchored protein from the egg plasma membrane results in greatly reduced fertilization rates without affecting sperm-zona pellucida binding [ 8 ] . Other egg surface molecules are the adhesion molecules NCAM, VCAM-1, ICAM-1 and ECAD [ 9 ] , and the selectins [ 10 ] . Additionally, the IgG receptor [ 11 ] , complement receptors C1q [ 12 ] , CD35 and CD11b, [ 13 ] and the Fc gamma receptors [ 14 ] exhibit oolemmal expression in a variety of mammalian species.

  • The three proteins that comprise the zona pellucida (ZP1, ZP2 and ZP3) and their roles in sperm-binding are well characterized [ 1 ] . In contrast, little is known about the surface proteins of the egg plasma membrane.

  • In primates SPAM1 has been shown to play a role in three functions during fertilization: (1) hyaluronidase enzyme activity necessary for penetrating the cumulus [ 3 ] and for which it is best known [ 4 ] , (2) zona pellucida binding [ 3 ] , and (3) Ca 2+signaling-associated acrosomal exocytosis [ 5 6 7 ] .


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