Example sentences for: pdgfr

How can you use “pdgfr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Over-expression of PDGFR has been reported in a variety of human tumors including glioma and glioblastoma, pancreatic and colonic cancers, breast, bone and ovarian tumors [ 11 ] . In normal cells, expression of PDGFR can be seen in the fibroblasts and the smooth muscle cells in the lung and airway [ 12 ] . There is so far to our knowledge no report to link the expression of PDGFR to lung cancer.

  • Moreover, we pre-treated C6-δ-OR cells with the IR antagonist, hydroxy-2-napthalenylmethylphosphonic acid-tris acetoxymethylester (HNMPA-(AM) 3 ; 100 μM), or the PDGFR antagonist, (tyrosphostin 9; 100 μM) before the addition of DSLET (1 μM).

  • The EGFR antagonist, AG1478 (4-(3-chloroanilino)-6,7-dimethoxyquinazoline), the insulin receptor antagonist, hydroxy-2-napthalenylmethylphosphonic acid-tris acetoxymethylester (HNMPA-(AM) 3 ), and the PDGFR antagonist, tyrosphostin, 9 were purchased from Biomol (Plymouth Meeting, PA).

  • EGFR, IR, or PDGFR) stimulate ERKs [ 22 23 ] , no single sequence of events appears to hold among GPCRs, even when they are expressed in the same cell line.

  • However, C6 glioma cells express additional RTKs including insulin (IR) and platelet-derived growth factor (PDGFR) receptors.


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