Words similar to pdgfr
Example sentences for: pdgfr
How can you use “pdgfr” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, neither of these proteins has been reported to act as a surrogate scaffold during ERK activation by non-opioid GPCRs [ 27 ] . In the present report, DSLET-mediated ERK phosphorylation was unaltered by the presence of the IR or PDGFR antagonists, HNMPA-(AM) 3 and tyrosphostin 9, respectively.
Gleevec was designed to inhibit the BCR-ABL tyrosine kinase, and it cross-reacts with c-kit and PDGFR [ 5 ] . In non-small cell lung cancer, BCR-ABL expression has never been reported, and it is unlikely that BCR-ABL fusion protein plays any role in lung cancer.
PDGFR expression in lung cancer
However, C6 glioma cells express additional RTKs including insulin (IR) and platelet-derived growth factor (PDGFR) receptors.
Moreover, we pre-treated C6-δ-OR cells with the IR antagonist, hydroxy-2-napthalenylmethylphosphonic acid-tris acetoxymethylester (HNMPA-(AM) 3 ; 100 μM), or the PDGFR antagonist, (tyrosphostin 9; 100 μM) before the addition of DSLET (1 μM).