Example sentences for: pdgfr

How can you use “pdgfr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • At concentrations of 10 μM, neither DSLET, DADLE, nor DPDPE were found to increase the tyrosine phosphorylation of the IR or the PDGFR, whereas insulin (100 ng/ml) or PDGF (50 ng/ml) induced significant tyrosine phosphorylation of these sites (Figure 8).

  • Over-expression of PDGFR has been reported in a variety of human tumors including glioma and glioblastoma, pancreatic and colonic cancers, breast, bone and ovarian tumors [ 11 ] . In normal cells, expression of PDGFR can be seen in the fibroblasts and the smooth muscle cells in the lung and airway [ 12 ] . There is so far to our knowledge no report to link the expression of PDGFR to lung cancer.

  • We have demonstrated that A549 cells express PDGFR α, one of the known potential targets for Gleevec effect.

  • However, C6 glioma cells express additional RTKs including insulin (IR) and platelet-derived growth factor (PDGFR) receptors.

  • EGFR, IR, or PDGFR) stimulate ERKs [ 22 23 ] , no single sequence of events appears to hold among GPCRs, even when they are expressed in the same cell line.


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