Words similar to pdgfr
Example sentences for: pdgfr
How can you use “pdgfr” in a sentence? Here are some example sentences to help you improve your vocabulary:
The PTK XXII (nematode kin15/16 related kinases) subfamily was not identified in the human genome, although members of the PDGFR and FGFR branches are about 30-35% identical to known nematode PTK XXII subfamily members.
PDGFR expression in lung cancer
We have demonstrated that A549 cells express PDGFR α, one of the known potential targets for Gleevec effect.
Since it has been reported that Gleevec can inhibit the function of PDGFR under the cell culture conditions, it is likely that Gleevec exerts its inhibitory effects on A549 lung cancer cells through inhibiting the PDGFR function.
Gleevec was designed to inhibit the BCR-ABL tyrosine kinase, and it cross-reacts with c-kit and PDGFR [ 5 ] . In non-small cell lung cancer, BCR-ABL expression has never been reported, and it is unlikely that BCR-ABL fusion protein plays any role in lung cancer.
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