Example sentences for: pdgf

How can you use “pdgf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Existing data suggest that Gleevec can exert its inhibitory effect on tumor cells through inhibiting PDGF receptor function, and we have shown that the primary non-small cells lung cancer expressed minimal c-Kit.

  • CMV = cytomegalovirus, MCMV = murine cytomegalovirus, MCP-1 = monocyte chemoattractant protein-1, PCNA = proliferating cell nuclear antigen, PDGF = platelet derived growth factor, SSc = systemic sclerosis, TGF-β 1 = transforming growth factor-β 1 , TUNEL = terminal TdT-mediated dUTP nick end labeling, α-SMA = α-smooth muscle actin

  • PDGF receptors are widely expressed in a variety of tissues, and the levels of expression in normal tissues are minimal.

  • The dependence of this increased turnover on phosphorylation of Rlk suggests that a phosphotyrosine-dependent association with another molecule may be required for this process, reminiscent of the increased degradation of the PDGF receptor and Syk caused by association with the ring-finger protein Cbl [ 47, 48, 49] or the Lck-dependent degradation of the TCR [ 50].

  • Adhesion to III1-C results in robust activation of ERK; comparable to that seen with PDGF stimulation.


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