Words similar to pdgf
Example sentences for: pdgf
How can you use “pdgf” in a sentence? Here are some example sentences to help you improve your vocabulary:
Perhaps this is a mechanism of ensuring paracrine, but not autocrine, effects of PDGF in cytokine-stimulated chondrocytes.
Gleevec has been shown to induce clinical, hematological and molecular remissions for CML patients [ 4 ] . It cross-reacts with two other important growth factor receptors containing tyrosine kinase domains, c-kit and PDGF receptors, that play important roles in growth and proliferation of a variety of cell types [ 5 ] . C-kit (also known as CD117) is frequently mutated in gastrointestinal stromal tumor (GIST), and the mutated c-kit shows higher tyrosine kinase activity.
Thus, the adhesion of RASMCs to III1-C resulted in robust activation of ERK1/2 that was comparable to the activation obtained with PDGF.
Western blotting analyses of PDGF receptors were performed using a previously described method [ 16 ] . Briefly, the tumor cells were treated with Gleevec at the various concentrations for 6 hours.
The elevated expression of PDGF in our model is also significant since the expression of these growth factors by endothelial cells can be induced by direct immune cell - endothelial cell interaction, promoting smooth muscle cell migration and proliferation in atherosclerosis [ 39 ] . CMV, as well as other viruses, induces expression of a number of cytokines and growth factors in cells in vitro, including TGF-β, a profibrogenic cytokine [ 40 41 ] . MCP-1 is a member of the β-chemokine (C-C) family [ 42 ] and this chemokine has been implicated in pathogenesis of SSc [ 43 ] . Our results (Fig.