Words similar to parp

Example sentences for: parp

How can you use “parp” in a sentence? Here are some example sentences to help you improve your vocabulary:

Instead, this amino-terminal mutation favored elevated caspase 3 levels that subsequently facilitated enhanced apoptosis by inactivating the caspase-dependent DNA repair proteins PARP and by inactivating DFF45, an inhibitor of the caspase-dependent DNase, DFF40.
This mutation, common among families with hereditary ovarian cancer, is a frameshift mutation occurring at the beginning of the C 3 HC 4 region of exon 2 that essentially interrupts RING domain function [ 19 29 30 ] . The results showed that disruption of the BRCA1 amino-terminal RING domain altered caspase 3 activation and subsequent DFF45 and PARP cleavage, resulting in accelerated STS-induced apoptosis.
Specifically, we evaluated the levels of activated c-Raf, ERK1/2, Caspase 3, and PARP using antibodies which identify only the phosphorylated or cleaved proteins and do not cross react with the inactive protein.
The finding of significant transmission distortion of marker alleles centromeric to PARP in the Minnesota collection suggests the possibility that the disequilibrium initially reported for PARP alleles may be due to more extensive disequilibrium - to include the PARP marker - in the families studied by Tsao and her colleagues compared with other populations and groups of families studied.
Interestingly, cleavage and inactivation of PARP was noted only at 3 h after STS treatment in BRCA1wt cells.