Example sentences for: parp

How can you use “parp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To determine which key pathways were activated, Western blot analyses of phosphorylated or cleaved proteins in E15+2 CONT and SN50-treated explants were conducted as previously described [ 5 ] . For this set of experiments, we first determined the specificity for each of the following antibodies purchased from Cell Signaling Technology (Beverly, MA) using E15 and E17 SMG homogenates: anti-phosphorylated Erk1/2 [phospho-p44/42 MAP kinase (Thr202/Tyr204)] antibody, anti-phosphorylated c-Raf(Ser259) antibody, anti-cleaved Caspase 3 (D 175) antibody, and anti-cleaved PARP (D214) antibody.

  • Human prototype serum containing highly specific antipolyADP-ribose polymerase (PARP) antibody and AGA sera were obtained from the serum bank of the WM Keck Autoimmune Center, The Scripps Research Institute, CA, USA.

  • 3, right), PARP was cleaved into an 89 kDa polypeptide (apoptotic fragments) or 60 and 50 kDa polypeptides (necrotic fragments), respectively, with complete degradation of native protein as previously described [ 24 ] . Golgin-160 was cleaved into 140 and 80 kDa fragments in apoptotic cells, consistent with published observations [ 29 ] . In contrast to the apoptotic fragments, a 70 kDa fragment was detected in necrotic cells.

  • AGA = anti-Golgi complex autoantibodies; H 2 O 2 = hydrogen peroxide; PARP = polyADP-ribose polymerase; PBS = phosphate-buffered saline; STS = staurosporine; zVAD-fmk = benzylocarbonyl-Val-Ala-Asp-fluromethylketone.

  • activated ERK1/2, Caspase 3, and PARP in SN50-treated explants (Fig.


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