Words similar to parp
Example sentences for: parp
How can you use “parp” in a sentence? Here are some example sentences to help you improve your vocabulary:
To determine which key pathways were activated, Western blot analyses of phosphorylated or cleaved proteins in E15+2 CONT and SN50-treated explants were conducted as previously described [ 5 ] . For this set of experiments, we first determined the specificity for each of the following antibodies purchased from Cell Signaling Technology (Beverly, MA) using E15 and E17 SMG homogenates: anti-phosphorylated Erk1/2 [phospho-p44/42 MAP kinase (Thr202/Tyr204)] antibody, anti-phosphorylated c-Raf(Ser259) antibody, anti-cleaved Caspase 3 (D 175) antibody, and anti-cleaved PARP (D214) antibody.
Human prototype serum containing highly specific antipolyADP-ribose polymerase (PARP) antibody and AGA sera were obtained from the serum bank of the WM Keck Autoimmune Center, The Scripps Research Institute, CA, USA.
3, right), PARP was cleaved into an 89 kDa polypeptide (apoptotic fragments) or 60 and 50 kDa polypeptides (necrotic fragments), respectively, with complete degradation of native protein as previously described [ 24 ] . Golgin-160 was cleaved into 140 and 80 kDa fragments in apoptotic cells, consistent with published observations [ 29 ] . In contrast to the apoptotic fragments, a 70 kDa fragment was detected in necrotic cells.
AGA = anti-Golgi complex autoantibodies; H 2 O 2 = hydrogen peroxide; PARP = polyADP-ribose polymerase; PBS = phosphate-buffered saline; STS = staurosporine; zVAD-fmk = benzylocarbonyl-Val-Ala-Asp-fluromethylketone.
activated ERK1/2, Caspase 3, and PARP in SN50-treated explants (Fig.