Words similar to parp

Example sentences for: parp

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Human prototype serum containing highly specific antipolyADP-ribose polymerase (PARP) antibody and AGA sera were obtained from the serum bank of the WM Keck Autoimmune Center, The Scripps Research Institute, CA, USA.
This mutation, common among families with hereditary ovarian cancer, is a frameshift mutation occurring at the beginning of the C 3 HC 4 region of exon 2 that essentially interrupts RING domain function [ 19 29 30 ] . The results showed that disruption of the BRCA1 amino-terminal RING domain altered caspase 3 activation and subsequent DFF45 and PARP cleavage, resulting in accelerated STS-induced apoptosis.
The data reported here provide some additional perspective on the initial reports that PARP might be the relevant gene in this locus.
Figure 3shows the results of immunoblotting analysis using antibodies to PARP and four Golgi autoantigens.
PARP (110 kDa protein) was selected as a positive control to monitor the cleavage of proteins during apoptosis and necrosis because its cleavage products in Jurkat cells undergoing apoptosis (89 kDa) and undergoing necrosis (60 and 50 kDa) are well established [ 20 24 30 ] .