Example sentences for: pannus

How can you use “pannus” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In view of the analogies between erosion formation in arthritis and tumor invasion in cancer, we hypothesized that activated MMP-2 and possibly MMP-9 might play an important role in the early stages of invasion of synovial pannus into bone and cartilage.

  • Although the pathologic processes that underlie the development of erosions are incompletely understood, a considerable body of evidence has suggested that a pannus of cells that originate in chronically inflamed, proliferative synovial tissue becomes locally invasive, and enzymatically degrades the matrix of the articular cartilage and periarticular bone [ 4].

  • It has been postulated that the locally invasive cells that form the aggressive pannus have acquired a transformed phenotype, and analogies to invasive cancer cells have been made [ 26].

  • In addition members of this subfamily of MMPs are involved in the invasiveness of cancers [ 15, 16], and thus may also play a similar role in the invasion of synovial pannus.

  • Although both of these MMPs are expressed at the junction between synovial pannus and cartilage or bone [ 14], further evidence of their direct role in erosion formation is lacking.


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