Words similar to oxide
Example sentences for: oxide
How can you use “oxide” in a sentence? Here are some example sentences to help you improve your vocabulary:
The regulation of lumenal diameter in large arteries is accomplished through the maintenance of shear stress along the arterial wall [ 38 50 51 52 53 54 ] . As blood flow through an artery increases, shear is also increased, and the endothelium releases nitric oxide for vasodilation [ 55 ] . Chronically, the arterial wall will remodel to a larger diameter to accommodate the increased flow [ 38 ] . While we did not measure arterial flow through these iron deficient arteries, the enhanced inotropic compensation to iron deficiency, combined with the enlarged aortic diameter, leads us to suspect a flow dependent mechanism for remodeling.
Nitric oxide metabolites
It was originally characterized as a powerful macrophage activator that upregulated nitric oxide (NO) production and MHC expression in macrophages [ 16 ] . It has since been shown to stimulate antiviral and antibacterial activities, to differentiate Th0 cells toward Th1 fates, and to activate endothelial cells for leukocyte adhesion (reviewed in [ 17 18 ] ).
These compounds can activate some nuclear receptors including steroidogenic factor 1 [ 44 ] and LXR, which may be partially responsible for their biological activities [ 45 46 ] . Cholesterol oxides are inhibitors of HMG-CoA reductase, the key enzyme of cholesterol biosynthesis pathway [ 47 ] . The ability to bind to an intracellular receptor, oxysterol binding protein, may be responsible for their inhibition of cholesterol biosynthesis [ 48 49 ] . It should be noted that addition of cholesterol does not prevent cholesterol oxide induced cell death, which leads to the suggestion that inhibition of cholesterol synthesis is not the cause of cholesterol oxide induced PCD [ 50 51 ] . The critical events that result in cholesterol oxide induced cytotoxicity remain to be determined.
Free-radicals ( e.g. , superoxide, hydroxyl radicals, nitric oxide and peroxynitrite) have long been thought to be a key element in the cellular dysfunction and death that are central to the pathogenesis of many aspects of diabetes.
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