Words similar to ossification

Example sentences for: ossification

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Each step of cartilage maturation occurs in a precise and tightly regulated manner [ 4 ] . Disruptions of this process cause abnormalities in cartilage and bone formation [ 5 6 ] . Endochondral ossification occurs in embryonic skeletal formation, in skeletal growth and fracture healing.
Similar results were reported by other authors [ 15 16 17 ] . These results demonstrate that the cultured rib chondrocytes behaved in a similar manner as chondrocytes in vivo . Taken together, primary rib chondrocytes from mouse neonates grown in micromass culture display cellular differentiation, proliferation, maturation and hypertrophy, recapitulating the chondrocyte maturation program in vivo . These results establish the utility of this in vitro system to investigate the role of Hox genes and other transcription factors in endochondral ossification.
Detailed knowledge of regulatory mechanisms in endochondral ossification will be essential for strategies to manipulate chondrocyte proliferation, differentiation and maturation in skeletal growth and development, osteochondrodysplasias and fracture healing.
Endochondral ossification is the process by which mesenchymal cells condense at specific sites and differentiate into chondrocytes, forming the cartilage anlagen that are the model for the future bone.