Example sentences for: oric

How can you use “oric” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Beginning with nucleotide number 1 in the dnaA coding region of each genome, a comparison of 2 million bases of M. paratuberculosis with 2 million bases from M. avium by Pustell DNA matrix analysis [ 25 ] , indicates that genomic similarity continues outside the surrounding oriC region (Fig.

  • While these sequencing efforts have revealed a conserved gene order in the oriC of Gram-positive bacteria [ 11 ] , the nucleotide and amino acid identity between M. paratuberculosis and M. avium in this region is much stronger when compared to other mycobacteria and other Gram-positive bacteria (see Table 2).

  • It is well recognized that the characterization of gene organization in the oriC region as well as the complete genome sequence will provide a springboard for addressing questions such as the nature of the slow growth rate of M. paratuberculosis as compared to the genetically related rapidly-growing mycobacteria.

  • Likewise, the oriC region in M. paratuberculosis was found to share a high level of nucleotide identity (~98%) with M. avium . Calculation of the rates of total nucleotide diversity (3) and synonymous substitution per synonymous site (ds) and non-synonymous substitution per non-synonymous site (dn) revealed patterns of variation within the range observed from sequence data outside the oriC region.

  • The sequence immediately flanking the dnaA gene is considered the origin of chromosomal replication, or oriC region [ 9 10 ] . This region contains several genes that encode proteins required for basic cellular functions, including the protein subunit of RNase P (RnpA), ribosomal protein L34 (RpmH), the replication initiator protein (DnaA), the beta subunit of DNA polymerase III (DnaN), the recombination repair protein RecF, and the DNA gyrase proteins GyrA and GyrB.

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