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Example sentences for: oric

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The M. paratuberculosis oriC region conforms to the conserved gene order that is present in other mycobacteria as well as the closely related Streptomyces coelicolor . Even the more distantly related Bacillus subtilis shows some degree of synteny in this region.
It is well recognized that the characterization of gene organization in the oriC region as well as the complete genome sequence will provide a springboard for addressing questions such as the nature of the slow growth rate of M. paratuberculosis as compared to the genetically related rapidly-growing mycobacteria.
While these sequencing efforts have revealed a conserved gene order in the oriC of Gram-positive bacteria [ 11 ] , the nucleotide and amino acid identity between M. paratuberculosis and M. avium in this region is much stronger when compared to other mycobacteria and other Gram-positive bacteria (see Table 2).
First, the putative oriC region of M. paratuberculosis was amplified, sequenced and compared with M. avium and other bacteria.
Because of strong similarity in the oriC region, alternative hypotheses should be tested to explain the growth rate differences between M. avium and M. paratuberculosis . Genomic rearrangements and the presence of unique genes identified by matrix analysis in this study are two such possibilities that could account for some of the phenotypic differences.