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Example sentences for: oric
How can you use “oric” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is well recognized that the characterization of gene organization in the oriC region as well as the complete genome sequence will provide a springboard for addressing questions such as the nature of the slow growth rate of M. paratuberculosis as compared to the genetically related rapidly-growing mycobacteria.
We next determined if the nucleotide identities would remain consistently high when M. paratuberculosis sequences outside the oriC region were compared with M. avium . Sequencing of the M. paratuberculosis K-10 cattle isolate is nearing completion in our laboratories and TIGR http://www.tigr.orgis in the finishing stages of M. avium isolate 104.
The genetic organization of the origin of replication has been characterized in several Gram-positive pathogens including B. subtilis , S. coelicolor , M. tuberculosis , M. avium , M. leprae , and M. smegmatis [ 8 ] . The results of our investigation on the oriC region of M. paratuberculosis show that each of the 15 primer pairs, designed from M. avium sequence data, resulted in the successful amplification and subsequent sequencing of an ~11 kb region of the M. paratuberculosis genome.
The M. paratuberculosis oriC region conforms to the conserved gene order that is present in other mycobacteria as well as the closely related Streptomyces coelicolor . Even the more distantly related Bacillus subtilis shows some degree of synteny in this region.
While these sequencing efforts have revealed a conserved gene order in the oriC of Gram-positive bacteria [ 11 ] , the nucleotide and amino acid identity between M. paratuberculosis and M. avium in this region is much stronger when compared to other mycobacteria and other Gram-positive bacteria (see Table 2).
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