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Example sentences for: oric

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The GenBank accession number for the M. paratuberculosis 11-kb oriC region is AF222789.
While these sequencing efforts have revealed a conserved gene order in the oriC of Gram-positive bacteria [ 11 ] , the nucleotide and amino acid identity between M. paratuberculosis and M. avium in this region is much stronger when compared to other mycobacteria and other Gram-positive bacteria (see Table 2).
The sequence immediately flanking the dnaA gene is considered the origin of chromosomal replication, or oriC region [ 9 10 ] . This region contains several genes that encode proteins required for basic cellular functions, including the protein subunit of RNase P (RnpA), ribosomal protein L34 (RpmH), the replication initiator protein (DnaA), the beta subunit of DNA polymerase III (DnaN), the recombination repair protein RecF, and the DNA gyrase proteins GyrA and GyrB.
Because of strong similarity in the oriC region, alternative hypotheses should be tested to explain the growth rate differences between M. avium and M. paratuberculosis . Genomic rearrangements and the presence of unique genes identified by matrix analysis in this study are two such possibilities that could account for some of the phenotypic differences.
An ~11-kb contiguous genomic fragment from M. paratuberculosis was amplified and sequenced using 15 primer pairs designed from M. avium genomic sequence in the putative oriC region (Fig.