Example sentences for: organelles

How can you use “organelles” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Owing to their long-term, stable transmission from generation to generation (vertical transmission), these cytoplasmic genomes have been viewed as analogs to organelles.

  • “It's not easy to see if selection [on organelles] is strong enough,” he says.

  • In addition, trophozoites are characterized by massive hemoglobin ingestion, intake of nutrients from the surrounding medium, increasing concentration of cytoplasmic ribosomes and rapid formation of organelles.

  • Rab proteins comprise a large family of Ras-related GTPases that function in the anterograde and retrograde trafficking of proteins in mammalian cells [ 1 2 3 ] . Different Rab proteins reside in specific subcellular membranes or organelles, where they mediate vesicular transport between discrete donor and acceptor compartments in the endocytic or exocytic pathways [ 4 5 ] . Detailed studies of a few Rab proteins ( e.g .; Rab1, Rab5 and Rab9) have led to a general model wherein Rab proteins are presumed to cycle on and off donor and acceptor membranes in connection with changes in their guanine nucleotide state [ 6 7 8 ] . In the active GTP-bound state, Rab proteins associate with budding transport vesicles [ 9 10 11 ] and appear to participate in the assembly of membrane docking complexes [ 12 13 14 ] . Following vesicle fusion with the acceptor compartment and GTP hydrolysis, the inactive GDP-bound Rab is extracted from the membrane by a carrier protein termed guanine nucleotide dissociation inhibitor (GDI) [ 15 16 17 ] . The GTPase can then re-enter the transport cycle through nucleotide exchange promoted by a specific exchange factor at the donor vesicle membrane [ 18 19 20 ] . In addition to changes in guanine nucleotide state, the posttranslational prenylation of Rab proteins plays an important role in the cycling mechanism.

  • The Ca 2+concentration in the cytoplasm ([Ca 2+] cyt ) is maintained in the nanomolar range (approximately 100-200 nM), whereas the concentration in organelles and cell wall is in the millimolar range [ 1, 3, 5, 6].


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