Words similar to orbitofrontal

Example sentences for: orbitofrontal

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One study demonstrated that single neurons in the macaque orbitofrontal cortex change their responses to a visual cue after a single trial in which the reward association of the visual cue is reversed (Thorpe et al.
These results strongly suggested a differential role for the lateral and medial parts of the orbitofrontal cortex.
We used functional magnetic resonance imaging to show that the ability to change behaviour based on facial expression is not reflected in the activity of the fusiform face area (which invariably appears to reflect only identity and not valence), but that general reversal learning is specifically correlated with activity in the lateral orbitofrontal and anterior cingulate/paracingulate cortices (as well as other brain areas, including the ventral striatum and the inferior precentral sulcus) (Kringelbach and Rolls 2003).
When the inferior prefrontal convexity and parts of the lateral orbitofrontal cortex (which is the ventral part of the prefrontal cortex over the orbits) (see Figure 1) were lesioned, the monkeys became significantly impaired with respect to object reversal learning.
There was also some evidence that humans with lesions to the orbitofrontal cortex have problems with reversal learning, but the lesions, caused by neurological insult, were not very clean or focal (Rolls et al.