Words similar to operonic
Example sentences for: operonic
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In either case, one would expect that the sequences encoded by the operonic genes of Anabaena would be the best matches for the operonic genes of Nostoc , as was indeed the case.
We evaluated whether the closest BLAST hits, using as queries the amino-acid sequences corresponding to the operonic genes of Anabaena or Nostoc , would be with other cyanobacteria (and therefore consistent with origin by gene duplication) or with another taxon grouping (consistent with LGT).
As BLAST hits must be considered imperfect indicators of nearest-neighbor homologs [ 38], the conclusion that the operonic trp -pathway genes are of cyanobacterial lineage origin was confirmed more rigorously by examination of extensive trees (available upon request) constructed for each trp protein of Anabaena and Nostoc . For the Trp-pathway proteins, all the cyanobacterial proteins clustered together, regardless of whether they were Anabaena or Nostoc paralogs or whether they were the singly represented proteins of Synechocystis, Synechococcus , or Prochlorococcus . The same result was obtained for AroA Iβ protein trees.
These include the overall gene organization of the trp operon, for which many microbial patterns are known; the extremely rare gene order of trpEa trpEb instead of the typical order trpEb trpEa; the fusion of genes encoding the alpha ( trpAa ) and beta ( trpAb ) subunits of anthranilate synthase, a fusion that exists in only a limited number of other taxa, and the presence of operonic genes exhibiting distinctive homology subtypes ( aroA Iβ and tyrA (p) ).
For all of the operonic Anabaena/Nostoc Trp-pathway proteins used as queries, homolog sequences from other cyanobacteria ( Synechocystis, Synechococcus, Prochlorococcus ) were the remaining top hits returned in the BLAST queue.