Words similar to oogonia
Example sentences for: oogonia
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Critical windows of activity in the sheep include: somatic ovarian tissue differentiation (from the gonadal ridges of the mesonephros) and growth (up to Day 50 of gestation); germ (from yolk sac endoderm) and pregranulosa (derived from the ovarian surface epithelium) cellular migration into and colonization of the ovaries (Days 30-65); clonal expansion of oogonia (Days 35-75); onset of meiosis and arrest (by Day 80) at the dictyate stage of prophase (the first division of meiosis is not completed until ovulation); and ovigerous cord regression and primordial follicle emergence (Days 65-110) [ 1 31 32 33 ] . It seems apparent that germ cells are particularly vulnerable to a metabolic insult when in the phasic transition between mitosis and meiosis I.
It has been suggested that oogonia which have matured to oocytes are less susceptible to degeneration as pregnancy advances [ 2 ] . A prominent role for the aromatic hydrocarbon receptor (e.g.
Fluorescence measurements of immunostained oogonia/oocytes
Results of this study indicate that in underfed ewes p53, Bcl-2, and polymerase β are up-regulated in fetal oogonia containing elevated contents of 8-oxoguanine.
In conclusion, we surmise that oxidative base damages to the DNA of fetal oogonia of pregnant animals faced with a nutritional adversity are a potential threat to the genetic character and reproductive capacity of their progeny; the predicament can evidently be reconciled by response mechanisms of cell-cycle arrest, survival, and repair.
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