Example sentences for: okadaic

How can you use “okadaic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The ability of okadaic acid to influence the intracellular partitioning of GR suggests that an okadaic acid sensitive ser/thr protein phosphatase (PPase) participates in the regulation of GR movement.

  • Okadaic acid inhibits the activity of PP5 in a dose-dependent manner, having an IC 50 of 5.58 +/- 0.41 nM.

  • In addition, okadaic acid, a potent inhibitor of PP1 activity [ 29 ] , significantly inhibits pRB dephosphorylation in this reaction.

  • Recent studies with okadaic acid suggest phosphorylation alters the high affinity binding of GR to hsp-90, and that an intact cytoskeleton is required for ligand-activated GR translocation through the cytoplasm to the nucleus [ 8].

  • Inhibition of phosphatase activity by okadaic acid was determined by adding the inhibitors to the enzyme mixture 10 minutes prior to initiating the reaction with the addition of substrate.


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