Words similar to okadaic
Example sentences for: okadaic
How can you use “okadaic” in a sentence? Here are some example sentences to help you improve your vocabulary:
[ 7] reported that treatment with okadaic acid, a potent ser/thr protein phosphatase inhibitor, also results in inefficient nuclear retention of agonist-bound GR and the cytoplasmic "trapping" of GR in a form that is unable to "recycle".
Okadaic acid is widely employed to inhibit PPase activity in eukaryotic cells, and the observed effects are often attributed to the inhibition of PP1 and PP2A.
However, due to toxicity and solubility constraints, in living cells it is difficult to distinguish the actions of PP2A from those of PP1 using okadaic acid.
Nonetheless, it is clear that PP5 is sensitive to inhibition by okadaic acid at the concentrations that also affects the activity of PP1 and PP2A.
Okadaic acid inhibits the activity of PP5 in a dose-dependent manner, having an IC 50 of 5.58 +/- 0.41 nM.
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