Words similar to okadaic

Example sentences for: okadaic

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Inhibition of phosphatase activity by okadaic acid was determined by adding the inhibitors to the enzyme mixture 10 minutes prior to initiating the reaction with the addition of substrate.
In addition, okadaic acid, a potent inhibitor of PP1 activity [ 29 ] , significantly inhibits pRB dephosphorylation in this reaction.
The marine toxin okadaic acid (OA), in particular, inhibits the PP2A class of phosphatases at sub-nanomolar concentrations (IC50 ~ 0.05 nM) and the PP1 class in the low nanomolar range (IC50 ~ 5-45 nM).
Based on titration studies with microcystin-LR to estimate the actual amount of PP5 in the reaction, an estimate of the K i for okadaic acid is 4.07 +/- 0.16 nM.
Okadaic acid inhibits the activity of PP5 in a dose-dependent manner, having an IC 50 of 5.58 +/- 0.41 nM.