Example sentences for: okadaic

How can you use “okadaic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [ 7] reported that treatment with okadaic acid, a potent ser/thr protein phosphatase inhibitor, also results in inefficient nuclear retention of agonist-bound GR and the cytoplasmic "trapping" of GR in a form that is unable to "recycle".

  • Okadaic acid is widely employed to inhibit PPase activity in eukaryotic cells, and the observed effects are often attributed to the inhibition of PP1 and PP2A.

  • However, due to toxicity and solubility constraints, in living cells it is difficult to distinguish the actions of PP2A from those of PP1 using okadaic acid.

  • Nonetheless, it is clear that PP5 is sensitive to inhibition by okadaic acid at the concentrations that also affects the activity of PP1 and PP2A.

  • Okadaic acid inhibits the activity of PP5 in a dose-dependent manner, having an IC 50 of 5.58 +/- 0.41 nM.


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