Example sentences for: okadaic

How can you use “okadaic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Inhibition of phosphatase activity by okadaic acid was determined by adding the inhibitors to the enzyme mixture 10 minutes prior to initiating the reaction with the addition of substrate.

  • Recent studies with okadaic acid suggest phosphorylation alters the high affinity binding of GR to hsp-90, and that an intact cytoskeleton is required for ligand-activated GR translocation through the cytoplasm to the nucleus [ 8].

  • Like calcineurin (PP2B) and PP2C, PP7 is apparently insensitive to inhibition by okadaic acid [ 20].

  • In vitro, okadaic acid acts as a potent inhibitor of serine/threonine protein phosphatases type 1 (PP1) and 2A (PP2A) [ 9, 10].

  • Therefore, when okadaic acid is employed to treat cells at a concentration of >1-5 nM, the activity of PP5 is also affected.


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