Words similar to okadaic

Example sentences for: okadaic

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To inhibit any endogenous PP2A activity, which can also dephosphorylate phosphorylase a and thus interfere with PP1 activity measurements, these assays were carried out in the presence of 5 nM okadaic acid, which does not inhibit PP1 activity [ 30 ] . Although reproducible, we observed only modest increases in PP1-specific activity found in lysates from induced cells compared to the uninduced controls (Figure 7).
[ 7] reported that treatment with okadaic acid, a potent ser/thr protein phosphatase inhibitor, also results in inefficient nuclear retention of agonist-bound GR and the cytoplasmic "trapping" of GR in a form that is unable to "recycle".
Nonetheless, it is clear that PP5 is sensitive to inhibition by okadaic acid at the concentrations that also affects the activity of PP1 and PP2A.
Okadaic acid sensitivity of PfPP5
Under identical assay conditions, okadaic acid is a more potent inhibitor of PP2A (IC 50 ~ 0.05 nM) and weaker inhibitor of PP1 (IC 50 ~ 45 nM).