Example sentences for: okadaic

How can you use “okadaic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Under identical assay conditions, okadaic acid is a more potent inhibitor of PP2A (IC 50 ~ 0.05 nM) and weaker inhibitor of PP1 (IC 50 ~ 45 nM).

  • Nonetheless, it is clear that PP5 is sensitive to inhibition by okadaic acid at the concentrations that also affects the activity of PP1 and PP2A.

  • In addition, okadaic acid, a potent inhibitor of PP1 activity [ 29 ] , significantly inhibits pRB dephosphorylation in this reaction.

  • The marine toxin okadaic acid (OA), in particular, inhibits the PP2A class of phosphatases at sub-nanomolar concentrations (IC50 ~ 0.05 nM) and the PP1 class in the low nanomolar range (IC50 ~ 5-45 nM).

  • Therefore, when okadaic acid is employed to treat cells at a concentration of >1-5 nM, the activity of PP5 is also affected.


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