Example sentences for: okadaic

How can you use “okadaic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Since PP5 is sensitive to inhibition by okadaic acid, we tested the possibility that PP5 acted at a more global level by assessing the effect of ISIS 15534 on the cellular distribution of NFAT-GFP.

  • In addition, okadaic acid, a potent inhibitor of PP1 activity [ 29 ] , significantly inhibits pRB dephosphorylation in this reaction.

  • [ 7] reported that treatment with okadaic acid, a potent ser/thr protein phosphatase inhibitor, also results in inefficient nuclear retention of agonist-bound GR and the cytoplasmic "trapping" of GR in a form that is unable to "recycle".

  • Recent studies with okadaic acid suggest phosphorylation alters the high affinity binding of GR to hsp-90, and that an intact cytoskeleton is required for ligand-activated GR translocation through the cytoplasm to the nucleus [ 8].

  • Aliquots of phosphorylated proteins were added to a reaction containing 120 μg cell lysate, recombinant human E1, 0.25 mg/ml ubiquitin, 1 μM ubiquitin aldehyde, 1 μM okadaic acid, 20 μM MG132, and ATP regenerating system (20 mM ATP, 10 mM creatine phosphate, 0.1 μg/ml creatine kinase).


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