Words similar to ogg

Example sentences for: ogg

How can you use “ogg” in a sentence? Here are some example sentences to help you improve your vocabulary:

However, as we also detected a significant increase in the islet area stained for Ogg1, we are confident that islet cell Ogg1 is actually upregulated in type 2 diabetes.
We conclude that the expression of the DNA repair enzyme Ogg1 is up-regulated in islets from type 2 diabetic specimens.
Unfortunately, there have been no studies of the effects of long-term chronic increases in oxidative DNA damage on Ogg1 expression.
Ogg1 knockout mice possess increased levels of 8-OH-dG in their genome, particularly in the mitochondrial genome, but do not seem to exhibit an increased frequency of malignancies [ 44 45 46 ] . It was postulated that the consequences of 8-OH-dG adducts and Ogg1 deficiency affects mainly cells with high oxygen metabolism and slow proliferation, such as liver cells [ 45 ] . While β-cells were not examined in that study, they certainly exhibit both high oxidative metabolism and a low rate of proliferation, consistent with them being a target for the effects of 8-OH-dG adducts.
The promoter of the Ogg1 gene does not have a TATA box [ 40 ] , but Ogg1 is differentially expressed in the rat CNS, and its expression is increased after mouse forebrain ischemia-reperfusion [ 35 36 ] , suggesting that regulation occurs, either at the transcriptional or post-transcriptional level.