Example sentences for: ogg

How can you use “ogg” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In light of the previous publication on the role of 8-OH-dG adducts in a rat model of type 2 diabetes [ 31 ] , and the finding that the Ogg1 gene was over-expressed in human type 2 diabetes, we evaluated the expression of Ogg1 protein in pancreas specimens from type 2 diabetic and healthy subjects, as a marker for β-cell oxidative DNA damage in type 2 diabetes.

  • We interpret the upregulation of Ogg1 as a response to an increased level of 8-OH-dG DNA, the lesion that it repairs.

  • Further epidemiological studies of Ogg1 expression as well as studies of the expression of other genes and proteins that are involved in DNA damage responses should also be performed to further test the hypothesis that DNA damage is involved in the pathogenesis of type 2 diabetes.

  • The association between the duration of diabetes and Ogg1 levels (Fig.

  • It would be of great interest to study the Ogg1 mutant mice to determine whether an increase level of 8-OH-dG adducts predisposes to diabetes.


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