Words similar to ogg
Example sentences for: ogg
How can you use “ogg” in a sentence? Here are some example sentences to help you improve your vocabulary:
In light of the previous publication on the role of 8-OH-dG adducts in a rat model of type 2 diabetes [ 31 ] , and the finding that the Ogg1 gene was over-expressed in human type 2 diabetes, we evaluated the expression of Ogg1 protein in pancreas specimens from type 2 diabetic and healthy subjects, as a marker for β-cell oxidative DNA damage in type 2 diabetes.
The promoter of the Ogg1 gene does not have a TATA box [ 40 ] , but Ogg1 is differentially expressed in the rat CNS, and its expression is increased after mouse forebrain ischemia-reperfusion [ 35 36 ] , suggesting that regulation occurs, either at the transcriptional or post-transcriptional level.
Interestingly, the Ogg1 fluorescent staining intensity, but not the percent positive islet area, increases with increasing duration of diabetes (Fig.
We interpret the upregulation of Ogg1 as a response to an increased level of 8-OH-dG DNA, the lesion that it repairs.
Sections were evaluated live in the fluorescence microscope with a combined filter for green and red fluorescence, which means that camera exposure time and other camera settings, did not influence the intensity of the Ogg1 staining.
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