Words similar to ogg

Example sentences for: ogg

How can you use “ogg” in a sentence? Here are some example sentences to help you improve your vocabulary:

In this study, both the area and the intensity of Ogg1 staining were assessed.
We conclude that the expression of the DNA repair enzyme Ogg1 is up-regulated in islets from type 2 diabetic specimens.
We noted that the variability in the amount of Ogg1 staining is higher in the control group than in the samples from the diabetic patients.
However, the nuclear localization of 8-OH-dG [ 32 ] and the increased Ogg1 reported here are consistent with a model in which mitochondrial Ogg1 is up-regulated but nuclear Ogg1 is not, leading to an increase in nuclear but not mitochondrial 8-OH-dG adducts [ 32 ] . Further studies will be required to resolve this issue, but β-cells in type 2 diabetes may well suffer from both nuclear and mitochondrial DNA damage, leading to decreased β-cell function and eventual loss of β-cell mass.
βOgg1 is an alternatively spliced form of Ogg1 that contains a mitochondrial targeting signal in the C-terminal portion of the protein [ 41 ] . Specific upregulation of mitochondrial but not nuclear Ogg1 occurs during aging in rodents [ 42 ] . A specific increase of Ogg1 in islet cell mitochondria is consistent with the idea that increased β-cell mitochondrial oxidative metabolism due to hyperglycemia is a major factor behind the DNA damage.