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Example sentences for: og-fe
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Despite the lack of detectable sequence similarity to 2OG-Fe(II) dioxygenases, these proteins contain a conserved HXH motif and a carboxy-terminal histidine that appear to be equivalent to the metal-chelating HXD and carboxy-terminal histidine of the latter (see above).
On the basis of the results of database searches with representative sequences, we delineated several distinct families within the 2OG-Fe(II) dioxygenase fold and constructed individual alignments for each using the ClustalW program [ 24].
The 2OG-Fe(II) dioxygenase protein superfamily: classification and functional prediction
The 2OG-Fe(II) dioxygenase superfamily is present in diverse bacteria that had probably diverged before the diversification of the eukaryotes that contain this superfamily.
The DSBH fold that comprises the core domain of the 2OG-Fe(II) dioxygenases is also present in a large number of proteins typified by the arabinose-binding domain of the transcription regulator AraC, plant seed proteins such as vicilin, and oxalate oxidase ([ 29]; see SCOP [ 12]).
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