Words similar to oedema
Example sentences for: oedema
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Because high doses of MG induce vomiting, oedema, dizziness and androgen-like side-effects, the ideal effective concentration is difficult to obtain in vivo . Therefore, the search for new drugs with low toxicity is in progress to meet an urgent need for clinical applications.
In Trinidad the following clinical features have been seen: tachypnea, restlessness, vomiting, increased salivation, cerebral oedema, pulmonary oedema, hypovolemic shock and convulsions, with myocarditis and pancreatitis being major complications [ 48 ] . Scorpion venoms may cause these symptoms through release of catecholamines from the sympathetic nervous system [ 11 ] . The venom exerts its effects primarily to the cardiovascular and respiratory systems, but there is also stimulation of both the sympathetic and parasympathetic peripheral activities [ 11 ] . The venom is a complex mixture of phospholipase A 2 , low molecular weight proteins, acetylcholinesterase, hyaluronidase, toxic polypeptides, amino acids, serotonin and neurotoxins [ 11 48 ] . Two fatal cases suggested toxic myocarditis [ 48 ] .
In the presence of alterations in the blood-brain barrier, injection of contrast material increases brain oedema [ 6, 7, 8, 9].
Infusion of fluids was continued in all patients with regard on comfort according to clinical signs of thirst with restriction of volumes in cases of oedema, ascites and pulmonary congestion.
Studies in South America detail the pain and oedema at the bite site and manifestations of autonomic nervous system stimulation (vomiting, diarrhoea, sweating, hypersalivation, bradycardia) that may be attributed to serine protease in Lachesis muta venom which causes hypotension by releasing kinins from plasma kininogen [ 8 ] . There are also cases of bleeding distant from the bite site such as gingival haemorrhage, epistaxis, haemoptysis, haematuria, uterine bleeding, soft tissue haematomas and very infrequently intrathoracic or intrabdominal bleeding [ 35 ] . Complications in the bitten limb can include secondary infections by Gram-negative organisms and acute renal failure among others [ 8 ] . There is a bothrojacarin-like 27 kDa protein in Bothrops species venom [ 36 ] . Bothrojacarin forms a non-covalent complex with thrombin, blocking its ability to induce platelet aggregation and fibrinogen clotting [ 8 36 ] . Haemostatic effects in Lachesis muta venom are attributable to an alpha-fibrin(ogen)ase and haemorrhagic metalloproteinases (LHF-1 and LHF-II) which have alpha-fibrin(ogen)ase activity [ 8 ] .
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