Words similar to obstacle

Example sentences for: obstacle

How can you use “obstacle” in a sentence? Here are some example sentences to help you improve your vocabulary:

In our experiments the concentration of plasmid preparations limited the maximal dose that could be delivered into the tumour, but If this technical obstacle of producing highly concentrated plasmid was solved, electroporation would offer an applicable transfection technique for viral-resistant tumours that are accessible with an electroporation device i.e. head and neck or skin cancers.
Congress found that a leading obstacle to expanding retirement saving has been that many Americans do not know how to save for retirement, let alone how much.
But the most formidable obstacle to online voting may be entrenched interests threatened by change.
To overcome this obstacle, most of the organizations required members to sign confidentiality or informationsharing agreements.
--From "Obstacle to Opportunity: How Acid Rain Emissions Trading is Delivering Cleaner Air", Environmental Defense, September 2000, p.