Words similar to obligatory
Example sentences for: obligatory
How can you use “obligatory” in a sentence? Here are some example sentences to help you improve your vocabulary:
, [ 27, 30] suggest that in IBD, iNOS blocks an early, obligatory phase of inflammation, but perhaps not the chronic phase.
In current American usage, the term resembles what we call kidding: that is, making fun of someone or some thing in a frivolous manner, such as in the obligatory banter at roasts of famous people.
In vitro experiments with rat GCs have demonstrated that BMP-4 and -7 inhibit and stimulate FSH-induced progesterone and estradiol production, respectively [ 4 ] . In related studies BMP-6 and BMP-15 were found to block FSH action through inhibiting FSH-dependent adenylate cyclase activity and FSH receptor expression, respectively [ 11 12 ] . The importance of these findings is underscored by the fact that FSH action is obligatory for normal folliculogenesis and female fertility.
In particular, the apparently obligatory roles of E204 and E194 in fast H +release in bR are not matched in pR.
The initial step of the insertion can proceed in the presence of either Mg.ATP or a non-hydrolyzable ATP-analog and involves oligomerization of the BchD and BchI subunits to form an oligomeric ring of AAA protomers that resembles the ring structure of NSF and other AAA proteins [ 14 32 ] . The second step of the insertion involves an obligatory hydrolysis of ATP that is tightly coupled with the transfer of the chelated Mg 2+to the protoporphyrin ring by BchH [ 49 ] . Although the details differ from midasin, particularly with respect to the subunit composition of the AAA ring, this chelation reaction provides a structural model suggesting that the function of the midasin M-domain may be to regulate the ATPase activity of the AAA protomers in the pseudo-hexameric ring and thus couple ATP hydrolysis to the binding of a protein ligand at the MIDAS site.
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