Words similar to ob
Example sentences for: ob
How can you use “ob” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although the mechanisms through which adrenalectomy acts to reverse obesity is not entirely clear, it is plausible that the mechanisms entail enhanced hypothalamic POMC production [ 6 ] . Hypothalamic POMC mRNA is reduced in several forms of obesity [ 18 19 20 ] . Conversely, reversal of obese phenotypes by adrenalectomy is associated with a restoration of hypothalamic POMC mRNA tone in leptin-deficient ob/ob mice [ 6 ] . Furthermore, the melanocortin agonist MTII (which mimics the key anti-obesity product of POMC, alpha-MSH) reduces body weight in diet-induced obesity [ 21 ] . On the other hand, the effect of diet-induced obesity on hypothalamic POMC mRNA is somewhat complex and may depend on the genetic background [ 22 23 ] , and duration of the diet [ 24 25 ] or composition [ 23 ] of the diet.
On the other hand, using the same adrenalectomy protocol that produced a similar reduction, but not elimination, of plasma corticosterone levels, we observed a remarkable reversal of obese phenotypes in leptin-deficient ob/ob mice [ 6 ] . Furthermore, the reduction of corticosterone by adrenalectomy in the present study was sufficient to produce elevation of pituitary POMC mRNA (as well as hypothalamic POMC mRNA), demonstrating that the reduced levels were clearly producing physiological effects.
The availability of extensive genome sequence data and advances in structure determination over recent years allow the successful application of comparative genomics, sequence and structure comparisons to identify any such folds that may be somewhat less widely represented than the OB or SH3-like folds.
Obese is a compound of two Latin words, the prefix, ob - `over' + ēdere `eat.
In this context it became clear that more information about OB+ADHD was needed and that wider exposure of this comorbidity would be valuable (and interesting) to clinicians treating obese patients.
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