Example sentences for: oa

How can you use “oa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Indeed, IL-1Ra gene therapy has demonstrated impressive efficacy in animal models of RA and OA, and a phase I human trial has recently confirmed that the human IL-1Ra cDNA can be safely transferred to and expressed within human rheumatoid joints [ 19 ] . A planned phase II study will determine the efficacy of this procedure.

  • ELISA = enzyme-linked immunosorbent assay; IP-10 = interferon-gamma inducible protein 10; mAb = monoclonal antibody; MCP-1 = monocytechemotactic protein-1; MIP = macrophage inflammatory protein; OA = osteoarthritis; PBMC = peripheral blood mononuclear cells; PE = phycoerythrin;RA = rheumatoid arthritis; RANTES = regulated upon activation, normal T cell expressed and secreted; RT-PCR = reverse transcriptase-polymerasechain reaction; SCL = stromal cell line; SRBC = sheep red blood cells; TNF-α = tumor necrosis factor-α.

  • Moreover, it is theoretically possible to regulate levels of IL-1Ra gene expression in a manner commensurate with disease activity [ 8 ] . IL-1Ra gene therapy has been evaluated in a number of different animal models of RA and OA, with extremely promising results [ 9 10 11 12 13 14 15 16 17 18 ] . Indeed, a phase I human study of IL-1Ra gene therapy in RA [ 19 ] was recently successfully completed.

  • [ 9], obesity is associated more strongly with bilateral than with unilateral hip OA [ 14].

  • This suggests that interventions to prevent overweight early in adulthood may mitigate the magnitude and prevalence of hip OA and its related disability.


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