Words similar to nrbvariants
Example sentences for: nrbvariants
How can you use “nrbvariants” in a sentence? Here are some example sentences to help you improve your vocabulary:
To insure that this observation was not the result of experimental manipulation, and indeed the nmt55/p54 nrbvariants detected with polyclonal antibody NMT-5 and monoclonal antibody NMT-1 but not polyclonal antibody NMT-4 were also expressed in intact cells, we utilized immunohistochemical analyses in human breast tumor tissue sections.
These results suggested the presence of nmt55/p54 nrbvariants in a subset of ER+ human breast tumors.
Our data suggests that nmt55/p54 nrbmay be critical to cell growth and function, such that, decreased nmt55/p54 nrbexpression in ER- human breast tumors or the expression of nmt55/p54 nrbvariants in ER+ tumors may indicate loss of normal growth, nmt55/p54 nrbhas been shown in several studies to bind RNA and interact with PSF and Topoisomerase I [ 14 16 17 18 19 20 39 ] . Those results along with our observations that nmt55/p54 nrbassociates with several splicing factors essential for spliceosome formation (unpublished) and relates to tumor hormonal status [ 13 ] suggest that nmt55/p54 nrbmay be involved in pre-mRNA processing.
We also wanted to determine if nmt55/p54 nrbvariants detected with polyclonal antibody NMT-5 and monoclonal antibody NMT-1 but not polyclonal antibody NMT-4 using nuclear extracts and Western blot analyses were also detectable in intact cells.
The observations made here further suggest the presence of nmt55/p54 nrbvariants in a subset of ER+ human breast tumors.