Example sentences for: nontypeable

How can you use “nontypeable” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Assays of 30 randomly chosen clinical isolates from the middle ear of children with otitis media and from the sputum of adults with COPD show that isolates of nontypeable H. influenzae demonstrate striking differences in their propensity to grow as biofilms in vitro.

  • Some authors have proposed that in otitis media with effusion, nontypeable H. influenzae grow in the form of a biofilm in the middle ear [ 15 22 23 ] .

  • Similarly, the epitopes recognized by monoclonal antibodies to outer membrane protein P5, an OMP A-like protein, and P6, a highly conserved protein in all strains of nontypeable H. influenzae , were expressed in the outer membranes of cells grown as biofilms and cells grown planktonically (Figure 4).

  • However, assays using the polymerase chain reaction (PCR) have demonstrated that DNA of nontypeable H. influenzae is present in a substantial proportion of these middle ear fluids [ 15 16 17 18 19 20 ] . Furthermore, reverse transcriptase PCR-based assays have shown the presence of bacterial mRNA, indicating that bacteria are present in a viable and metabolically active but non-culturable state [ 21 ] . These observations suggest that in otitis media with effusion, bacteria are in a physiological state which differs from that of bacteria growing planktonically in a free floating phase.

  • This paper is the first report of formation of biofilms by H. influenzae . Work on biofilm formation by nontypeable H. influenzae should focus in several areas.


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