Words similar to nonsynonymous
Example sentences for: nonsynonymous
How can you use “nonsynonymous” in a sentence? Here are some example sentences to help you improve your vocabulary:
451; r 2= 0.553), suggesting that the base composition of nonsynonymous sites in LTG is mainly the result of mutational pressures, and hence that their amino-acid composition is exceptionally affected by the constraints acting on the nucleotide sequence.
When-in house sequencing was done to verify nonsynonymous changes found in the in silico alignment, a minimum of two forward reads and two reverse reads was run for each sample of PCR products.
The strength of the selection on a given gene relative to the mutation pressure can be estimated by the method of the relative neutrality plot (RNP), which gives indications on how 'neutral' a coding sequence can be considered [ 18 19 ] . The method consists of plotting the G+C content at the constrained (or nonsynonymous) positions (that is, first and second positions) of the codons against the G+C content at the relaxed (or synonymous) position (that is, third position).
A search of Celera's SNP database found approximately half of the nonsynonymous B6/D2 sequence changes which we identified by multiple alignment of BLAST hits.
In all genomes analyzed, the nonsynonymous substitution rate was significantly lower than the synonymous substitution rate, such that K n /K s << 1 (Figure 1a,band Table 1), in agreement with the recent genome-wide study of paralogs [ 21].