Words similar to nonsynonymous

Example sentences for: nonsynonymous

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In total, 21 of the 199 genes surveyed from the chromosome 1 and 13 QTL regions showed nonsynonymous changes in their coding regions between B6 and D2 animals (Table 1).
The strength of the selection on a given gene relative to the mutation pressure can be estimated by the method of the relative neutrality plot (RNP), which gives indications on how 'neutral' a coding sequence can be considered [ 18 19 ] . The method consists of plotting the G+C content at the constrained (or nonsynonymous) positions (that is, first and second positions) of the codons against the G+C content at the relaxed (or synonymous) position (that is, third position).
There was also a correlation between the regions of homology to Ps-moeZ and the areas where synonymous substitutions exceeded nonsynonymous substitutions (Figure 2aand 2b).
In all genomes analyzed, the nonsynonymous substitution rate was significantly lower than the synonymous substitution rate, such that K n /K s << 1 (Figure 1a,band Table 1), in agreement with the recent genome-wide study of paralogs [ 21].
When-in house sequencing was done to verify nonsynonymous changes found in the in silico alignment, a minimum of two forward reads and two reverse reads was run for each sample of PCR products.