Example sentences for: nonsynonymous

How can you use “nonsynonymous” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The plot of the ratio of synonymous/nonsynonymous substitutions (dS/dN) identified five regions where the synonymous substitution rate exceeds the nonsynonymous substitution rate (dS / dN > 1), suggesting that homology in these areas was driven by the need for AA conservation (Figure 2b).

  • In all genomes analyzed, the nonsynonymous substitution rate was significantly lower than the synonymous substitution rate, such that K n /K s << 1 (Figure 1a,band Table 1), in agreement with the recent genome-wide study of paralogs [ 21].

  • Using a codon-based alignment of the NA sequences in the high homology group, we analyzed the occurrence of synonymous and nonsynonymous substitutions over the entire coding region.

  • In particular, rates of nonsynonymous substitution per site (resulting in an amino acid change; d N ) often greatly exceed those of synonymous substitution per site (silent change; d S ), as expected if most mutations are fixed because they increase fitness (Figure 1).

  • There was also a correlation between the regions of homology to Ps-moeZ and the areas where synonymous substitutions exceeded nonsynonymous substitutions (Figure 2aand 2b).


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