Example sentences for: nondisjunction

How can you use “nondisjunction” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, only about 50% of diploid meiotic products from rec12-D15 (null) mutant meioses were heterozygous for centromere linked markers (Figure 5E), indicating that some fraction of the products were derived from precocious separation of sister chromatids (PSS) and/or MII nondisjunction (Figure 5C, 5D).

  • Thus, those meioses did not exhibit simple MI nondisjunction, because 100% of diploids arising from MI nondisjunction would be heterozygous at the centromeres (Figure 5B).

  • In the absence of crossover recombination (chiasmata) and a backup distributive (achiasmatic) system for chromosome segregation, MI nondisjunction should occur and 100% of any resulting diploid spore colonies would be heterozygous for centromere linked markers (Figure 5B).

  • Although they exhibit a striking difference in their apparent MI nondisjunction frequencies, the rec12-D15 (null) and rec12-Y98F (active site) mutants manifest at most a two-fold difference in the absolute frequency of meiotic diploids exhibiting MII missegregation patterns (Figures 4, 5, Table 2).

  • First, Rec12 may be required for an "MI nondisjunction checkpoint" that delays meiotic cells in which proper MI disjunction has failed to occur.


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