Words similar to nondisjunction
Example sentences for: nondisjunction
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This role for Rec12 in equational chromosome segregation may be conserved, as spo11 mutants of Sordaria macrospora also exhibit frequent MII nondisjunction (S.
In the absence of Rec12 protein and crossovers, a backup distributive (achiasmatic) segregation system operates successfully on up to half of the chromosomes that would otherwise undergo MI nondisjunction.
Although they exhibit a striking difference in their apparent MI nondisjunction frequencies, the rec12-D15 (null) and rec12-Y98F (active site) mutants manifest at most a two-fold difference in the absolute frequency of meiotic diploids exhibiting MII missegregation patterns (Figures 4, 5, Table 2).
However, the frequency of MI nondisjunction observed is only half of that expected, suggesting the presence of a distributive (achiasmatic) system of chromosome segregation.
By applying mapping functions for aneuploid meiotic products [ 47 ] , we can set a lower limit of 22% and 29% MII nondisjunction for the rec12-117 and rec12-D15 meioses analyzed, respectively.
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