Words similar to noncanonical

Example sentences for: noncanonical

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Previous reports of ectopic expression of different Wnts in C57mg cells demonstrated Wnt-1 to be highly transforming whereas Wnt-5a failed to induce transformation [ 15 16 ] . By identifying downstream targets of Wnt-5a and Rfz-2, we wanted to determine which genes are responsible for these phenotypic changes as well as which genes might be targets of noncanonical Wnt signaling.
We overexpressed Rfz-2 in addition to Wnt-5a in C57mg cells in order to augment the activation of noncanonical Wnt signaling.
In addition, other plant miRNAs may proceed through precursors of noncanonical structure, such as multiple stem-loops or stem-loops of poor quality [ 14 ] . The existence of these types of pre-miRNAs in metazoans is unknown at present.
Such noncanonical structures may not be restricted to oligodeoxyribonucleotide arrays.
Previously identified genes regulated by Wnt signaling in this list include fibronectin [ 17 ] , IL-6 [ 18 ] , BMP-4 [ 19 ] , groucho related protein [ 20 ] , and Krox-20 [ 21 22 ] . Since Wnt-5a may couple to more than one frizzled receptor, different Wnt signaling pathways may be activated by Wnt-5a depending on the endogenous expression of various frizzled receptors [ 6 10 ] . Thus, it is possible that the gene expression pattern we identified may be due to the activation of both canonical and noncanonical Wnt signaling pathways.