Words similar to nonamer
Example sentences for: nonamer
How can you use “nonamer” in a sentence? Here are some example sentences to help you improve your vocabulary:
We were able to align the canonical RSS nonamer and Sb with this PSSM.
While 62% (219/356) of these RSS contain a consensus heptamer, just 16% (57/356) contain a consensus nonamer and only 13% (48/356) contain both a consensus heptamer and a consensus nonamer.
Potentially, the DNA binding domains of KRC might interact with the range of heptamer and nonamer sequences found in endogenous antigen receptor loci.
For example, the KRC/ZAS-C consensus sequence "ATTTTGTGG" matches completely with 6 nucleotides of the RSS nonamer and 3 flanking nucleotides of the human IgH D1, D2, D3 and D4 gene segments [ 35 ] . Furthermore, the MAST search identified KRC-selected motifs near two chromosomal breakpoints: between a t(11:14) translocation of the Ig DH2-2 gene segment and the B cell lymphoma 1 ( BCL-1 ) gene in a mantle cell lymphoma [ 36 ] , and at a t(11:19) translocation of the myeloid lymphoid leukemia ( MLL ) gene and the ENL/MLLT1/LTG19 gene in a T-cell acute lymphoblastic leukemia [ 37 ] . The other hits were derived from loci of cellular genes, pseduogenes, or DNA fragments [ 41 42 43 44 ] . The expression of those genes has not been shown to be regulated by KRC or other family members, therefore, the biological significance of those MAST results is unknown.
Furthermore, we were able to align the κB motif, the Sb sequence, the RSS nonamer, and part of the RSS heptamer "TGTG" with both PSSMs (Figs.