Words similar to non-nerve
Example sentences for: non-nerve
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Voltage-gated K +channels in non-nerve, non-muscle cells play crucial roles in cell development, proliferation, migration, volume regulation, as well as maintenance of membrane potential and cell viability.
This is in part because these channels regulate the cytoplasmic concentrations of K +, Ca 2+, and Na +ions [ 1 2 3 4 5 6 7 8 9 10 ] . The diversity of voltage-gated K +channels and currents present in these "non-excitable" (non-muscle, non-nerve) cells is impressive.
Hormonal signal transduction and steroidogenesis can be affected by changes in intracellular and extracellular concentrations of inorganic ions, cellular resting membrane potential, and cell size [ 29 30 35 54 55 56 57 58 59 ] . Blockade of 4-AP sensitive K +channels in non-nerve, non-muscle cells can lead to changes in transmembrane ion gradients, membrane potential and cell volume [ 42 60 ] . On this basis, we determined the effects of 24 h exposure to 4-AP on GC size, membrane potential and intracellular potassium ([K +] in ).
Data obtained previously in our laboratory suggest that inhibition of granulosa I Kur should be associated with a +10 to +20 mV depolarization of cell resting membrane potential; block of I Ks alone decreased resting potential by +10 mV while block of both I Ks and I Kur decreased resting potential by +20 to +30 mV [ 18 ] . Most previous investigations of 4-AP effects on the resting membrane potentials of non-nerve, non-muscle cells have similarly demonstrated drug-induced depolarization [ 42 60 ] , although there is a single report showing 4-AP-induced hyperpolarization of chondrocyte membrane potential [ 62 ] .
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