Words similar to non-human
Example sentences for: non-human
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Human and non-human sequences from the alignment were used as bait to reduce the probability of missing human members of subfamilies that are poorly represented in humans.
Thus, the gene-expression profile in this non-human primate model could provide useful insights into genes regulated in asthma and the mediators produced, although there is no evidence that the antigen used in this study would produce the same allergic reaction in humans.
Primarily examined through the use of G-banding cytogenetic techniques, the human and common chimpanzee karyotypes differ by only 10 euchromatic rearrangements: a telomere fusion between PTR chromosomes 12 and 13, resulting in HSA chromosome 2, and 9 pericentric inversions (HSA 1, 4, 5, 9, 12, 15, 16, 17, 18) [ 1 2 ] . The predominance of pericentric inversions between chimps and humans highlights their potential importance in the divergence of human from non-human primate species, and provides an opportunity to investigate the mechanism facilitating these rearrangements.
Several mechanisms of genetic change are thought to lead to speciation, including gene evolution via coding sequence mutation, gene expression variation by regulatory element mutation and chromosomal rearrangement - which has the potential to create reproductive barriers and induce genetic isolation within an existing population [ 6 ] . Although a thorough determination of all genetic differences between humans and our closest non-human primate relatives will not be possible until the genomic sequences of great ape species have been determined, many of the chromosomal rearrangements between great apes have been previously characterized at the cytogenetic level.
The allergic cynomolgus monkey ( Macaca fascicularis ) has been used as a non-human primate model to study inflammatory responses in the lung following allergen challenge [ 12, 13].
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