Example sentences for: non-covalent

How can you use “non-covalent” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the case of the EPO agonists, X-ray crystallographic analysis revealed that one of these peptides spontaneously formed non-covalent homodimers that allowed the dimerization of two EPO receptors.

  • [ 26 ] Furthermore, the rapid inhibition of plasmin requires a non-covalent interaction between an amino-terminal site of plasmin and a carboxyl-terminal on anti-plasmin, and a second site outside the RCL of PAI-1 contributes to its specific interaction with proteases.

  • Studies in South America detail the pain and oedema at the bite site and manifestations of autonomic nervous system stimulation (vomiting, diarrhoea, sweating, hypersalivation, bradycardia) that may be attributed to serine protease in Lachesis muta venom which causes hypotension by releasing kinins from plasma kininogen [ 8 ] . There are also cases of bleeding distant from the bite site such as gingival haemorrhage, epistaxis, haemoptysis, haematuria, uterine bleeding, soft tissue haematomas and very infrequently intrathoracic or intrabdominal bleeding [ 35 ] . Complications in the bitten limb can include secondary infections by Gram-negative organisms and acute renal failure among others [ 8 ] . There is a bothrojacarin-like 27 kDa protein in Bothrops species venom [ 36 ] . Bothrojacarin forms a non-covalent complex with thrombin, blocking its ability to induce platelet aggregation and fibrinogen clotting [ 8 36 ] . Haemostatic effects in Lachesis muta venom are attributable to an alpha-fibrin(ogen)ase and haemorrhagic metalloproteinases (LHF-1 and LHF-II) which have alpha-fibrin(ogen)ase activity [ 8 ] .

  • The trans actors assumed are a loose, non-covalent complex between the binder/cutter enzyme and telomerase, and a resecting exonuclease that pauses.

  • Mutational studies provided the initial hints that disruption of the non-covalent clasp between α and β cytoplasmic tails is clearly the event within the structure of the integrin that initiates inside-out signaling.


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