Words similar to non-allelic
Example sentences for: non-allelic
How can you use “non-allelic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Here, combining a master locus (C73) with a non-allelic singlet locus possessing 100% sequence identity (L91) resulted in immediate trans-silencing, as seen by a reduction of GFP-COP1 expression and block of cosuppression, which was stably maintained in the presence or absence of the master locus.
For example, an inverted repeat allele of the tryptophan biosynthetic gene PAI resident in the WS ecotype of Arabidopsis silences homologous PAI alleles, as well as unlinked PAI genes, from the Columbia ecotype [ 2 ] . Likewise, complex synthetic transgenes composed of PAI inverted repeats were able to trans-methylate homologous, yet non-allelic, target loci [ 12 ] . Similar events have been observed in other species [e.g.
Paramutation has been studied extensively for four maize loci that encode transcriptional regulators of pigment biosynthesis [ 1 ] . Paramutation has also been investigated in the Arabidopsis PAI gene family, at the a1 and chalcone synthase (CHS) transgene loci in petunia, and in a number of other cases [ 2 3 4 ] . The Arabidopsis resistance gene BAL/CPR1 displays a related form of epigenetic instability [ 5 6 ] . Interactions resembling paramutation also occur among non-allelic transgene loci with DNA sequence homology.
Second, the imprint left on the L91 locus by the C73 trans-silencer did modify L91's epistatic interaction with a non-allelic target locus, E82, as seen in the F1 generation.
These data suggest that the competence for trans-silencing may be transferred between non-allelic transgenes, reminiscent of the allelic transfer of epigenetic activity during paramutation.
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