Words similar to noggin
Example sentences for: noggin
How can you use “noggin” in a sentence? Here are some example sentences to help you improve your vocabulary:
The chimeric protein containing BMPR-IA was chosen because it has been previously reported that this is the predominant BMP receptor type expressed in embryonic and postnatal superior cervical ganglia (SCG) [ 29 ] . As indicated in Figure 5, follistatin and noggin significantly inhibit the dendrite promoting activity of BMP-5 in a concentration-dependent manner.
noggin, chordin, twisted gastrulation), while dominant negative receptor molecules (e.g.
For example, follistatin binds both activin and BMP-7 avidly but competes weakly or not at all with the type I receptor for BMP-4 binding [ 25 45 ] , whereas noggin binds to BMPs -2 and -4 with greater affinity than BMP-7 [ 46 ] . Whether BMP-5 function can be antagonized by noggin or follistatin has not been previously reported, but our results suggest that simultaneous addition of either antagonist with BMP-5 significantly inhibits the dendrite-promoting activity of BMP-5 in a concentration-dependent manner.
Groggo Noggin
Recent data suggest that in the developing nervous system, signaling by at least BMPs 2, 4 and 7 is determined by the spatiotemporal expression patterns of BMPs and their receptors, and by relative levels of the soluble BMP antagonists such as follistatin and noggin that directly bind BMPs in the extracellular compartment and prevent functional receptor/ligand interaction [ 1 24 25 26 27 28 ] . The extent to which these factors may regulate BMP-5 signaling is difficult to determine because of the paucity of data regarding either antagonism of BMP-5 signaling by follistatin and noggin or the interaction between known BMP receptors and BMP-5.
Loading...