Words similar to nnr

Example sentences for: nnr

How can you use “nnr” in a sentence? Here are some example sentences to help you improve your vocabulary:

Using two different RSV gene mRNAs as targets, and another NNR virus (VSV) as well as cellular mRNAs as controls, we show that synthetic dsRNA molecules are highly efficient and specific silencers of cytoplasmic RNA viral gene expression.
The overall steps of a NNR viral macromolecular synthesis in the infected cell are relevant for this paper, and are briefly described here [ 3 ] . The L protein is believed to encode the basic RNA polymerization function, and binds to the viral promoter at the 3' end of the genomic RNA to initiate transcription.
These obstacles have been largely circumvented by the use of cloned viral cDNA that is then altered by standard DNA-based site-directed mutagenesis procedures [ 8 9 ] . Originally designed for influenza virus minigenomes [ 10 ] , such cDNA-based "reverse genetics" strategy has been adopted in a large number of NNR viruses, including vesicular stomatitis virus (VSV), respiratory syncytial virus (RSV), and measles, to name a few [ 11 12 13 14 ] . Recently, extension of this approach has resulted in the cloning of full-length viral cDNA capable of producing infectious recombinant virus particles upon transcription.
Since NNR viruses co-opt the cellular translation machinery, the interferon response thus causes severe inhibition of viral translation.
Thus, we predict that an even lower concentration of dsRNA, perhaps in the sub-nanomolar range, might be able to destroy NNR viral mRNAs that are rarer, such as those of RSV M2 and L proteins.