Words similar to nlpc

Example sentences for: nlpc

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This suggests that despite the absence of significant sequence similarity, the NlpC/P60 domain is likely to contain a structural core corresponding to the classical papain-like protease fold (Figure 2).
The NlpC/P60 superfamily has diversified into four major families, with two of them - namely the LRAT and YaeF/Poxvirus G6R families - showing a circular permutation of the catalytic domain.
A comparison of the conserved residues and predicted secondary structure of the 'regular' NlpC/P60 domain with the permuted versions suggests that the five-stranded β-barrel is maintained intact, with the remaining segment including the helix with the cysteine being linked to either the amino or carboxyl terminus of the barrel (Figures 1, 2).
The observation that the three-stranded unit of the NlpC/P60 domain is followed by two other β-strands, suggests that the NlpC/P60 proteins are likely to form a five-stranded barrel similar to that seen in papain-like proteases (Figures 1, 2).
In the NlpC/P60 domains of the AcmB-like divergent group and the circularly permuted YaeF-like and poxviral groups, this residue is an acidic residue, as in most other thiol peptidases (Figure 1).