Words similar to nlpc
Example sentences for: nlpc
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Functional, architectural and phylogenetic diversity of the NlpC/P60 superfamily
MM2478 is a rare instance of an NlpC/P60 superfamily member occurring in the archaeal lineage.
Interestingly, the eukaryotic versions typified by the LRAT, their viral homologs and the bacterial forms typified by E. coli YaeF, while containing all the hallmark signatures of the NlpC/P60 catalytic domain, showed a reversal in the positions of the motifs with the conserved cysteine and the conserved histidine in their primary structures (Figures 1, 2).
The NlpC/P60 domain is predicted to adopt a papain-like fold, in which the catalytic cysteine is at the amino terminus of a helix, which is packed against a five-stranded β-barrel with the histidine and the polar residue.
The NlpC/P60 domain is also fused to other catalytic domains such as the polysaccharide-hydrolyzing lysozyme domain, and the JAB domain that has recently been described to have metallopeptidase activity [ 53, 54].
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