Words similar to nkb
Example sentences for: nkb
How can you use “nkb” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, in the rat, those authors did not find either NKA nor NKB in the dorsal motor nucleus of the vagus and in the nucleus prepositus hypoglossi, in which, in humans, we observed NK-ir structures.
Several studies have shown the distribution of NKA (preprotachykinin A mRNA) [ 12 ] and NKB (peptide-2; preprotachykinin B mRNA) [ 14 16 17 20 ] in the CNS of the rat.
Thus, the antibody used, in the present work, principally recognizes NKA but shows some cross-reactivity with NKB.
Our data are in agreement with previous results described in the rat brainstem, using radioimmunoassay techniques [ 29 30 ] . Thus, these latter authors found higher levels of NKA and lower levels of NKB in both the midbrain and the medulla oblongata of the rat [ 30 ] . In both regions of the human brainstem, we observed a high density of NK-ir structures.
It is also known that the biological actions of NKA, NKB and SP are mediated by three receptors, named neurokinin (NK)-1, NK-2 and NK-3 [ 2 ] . Thus, the tachykinins have been implicated in several physiological actions such as salivation, the regulation of smooth muscle contraction, depolarization of central neurons, hyperactivity, interaction with dopaminergic A-10 neurons mediating behavioral activation, regulation of blood pressure, and the transmission of the baroreceptor reflex [ 3 4 5 6 7 ] . In addition, a loss of tachykinin-containing neurons has been described in neurodegenerative diseases [ 8 ] , suggesting that the decrease in the amount of tachykinins could be involved in these and other diseases [ 9 10 ] .
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