Words similar to nfatp

Example sentences for: nfatp

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In unstimulated T cells NFATp exists in a highly phosphorylated form that when analyzed by SDS-PAGE has an apparent molecular weight that is significantly larger than its predicted molecular weight [ 2, 22, 26].
This was confirmed by performing mass spectrometry on peptides recovered from a tryptic digest of recombinant NFATp (W.
The PCR product was digested with Xba I and Mro I and ligated into pBS-KS +-NFATp that had been digested with Xba I and Mro I. pVL1392-HAX-NFATp(1-722) was made by subcloning a Nde I - Msc I fragment from pBS-KS +-NFATp(NdeI) into the Nde I and Sma I sites of pVL1392-HAX.
We chose to begin our analysis of NFAT proteins in vitro by working with human NFATp (B isoform, amino acids 1-921, Figure 1A).
In the case of T cells, antigen stimulation elicits a calcium-dependent signaling pathway that results in the activation of calcineurin, which directly dephosphorylates NFATp in preparation for nuclear import [ 11, 22].