Words similar to neuropathic
Example sentences for: neuropathic
How can you use “neuropathic” in a sentence? Here are some example sentences to help you improve your vocabulary:
In general, we found that genes that are enriched in the dorsal spinal cord are not among those found to be up-regulated in the spinal nerve ligation model of neuropathic pain (Table 3).
Although neuropathic pain may respond well to opioids, adjuvant analgesics (tricyclic antidepressants, anticonvulsants, antiarrhythmics, etc) are often required in combination with opioids to achieve adequate relief.
Despite advances in antiviral therapy during acute herpes zoster and the more recent introduction of vaccination against varicella zoster, PHN continues to be a significant clinical problem, with 10–20% of patients developing persistent neuropathic pain after acute herpes zoster reactivation.
We then further characterized the cellular localization of a subset of these genes in the spinal cord, as well as the regulation of a subset of the genes in a neuropathic pain model.
Several of these changes are maladaptive in the sense that they contribute to the generation of the abnormal sensations that constitute neuropathic pain, by producing ectopic spontaneous activity into the CNS, altering synaptic drive, increasing excitability and diminishing inhibitory action in the dorsal horn of the spinal cord, and by making novel synaptic contacts with inappropriate neurons [ 1 4 ] . A number of the injury-regulated genes we describe here may contribute directly to this altered sensory processing; CB1 receptor, VGF, the phospholemman ion channel, SNAP25 A, endothelin-1 and the ligand-gated 5-HT3 receptor (Table 4, see additional file 3).
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