Example sentences for: neurofilament

How can you use “neurofilament” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [ 12 ] , using the SMI-31 monoclonal antibody (mAB) to identify phosphorylated neurofilament proteins, reported discrete SMI-31 labeling within nuclei of SH-SY5Y neuroblastoma cells.

  • Dendritic growth was assessed in cultures immunostained with monoclonal antibodies (mAb) previously shown to react selectively with the somatodendritic compartment of cultured sympathetic neurons [ 16 ] . These mAb's include SMI-52, which is specific for the cytoskeletal protein MAP2, and SMI-32, which reacts with the non-phosphorylated forms of the M and H neurofilament subunits (Sternberger Immunocytochemicals, Baltimore, MD).

  • Screening of the translated non-redundant database at GenBank with the amino acid sequence of the yeast D/E-rich domain selected numerous other aspartate-glutamate rich proteins, including neurofilament proteins and caldesmon.

  • Both antibodies recognize phosphorylated variants of neurofilament.

  • SH-SY5Y cells are a subclone of the SK-N-SH human neuroblastoma cell line derived from neoplastic neural crest cells and under certain growth conditions, generate neuritic processes [ 12 13 ] . Sternberger and Sternberger [ 14 ] describe SMI-31 mAB as specific for phosphorylated epitopes on the heavy neurofilaments peptide (NF-H) and to a lesser extent medium neurofilament peptide (NF-M).


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