Words similar to neurodegenerative
Example sentences for: neurodegenerative
How can you use “neurodegenerative” in a sentence? Here are some example sentences to help you improve your vocabulary:
Such expansion of the polyQ domains in certain neuronal proteins could cause neurodegenerative disorders, e.g., Huntington's disease or several forms of ataxia.
Recently, much attention has been given to the neuroprotective properties of estrogens for both chronic neurodegenerative diseases and acute insults such as stroke.
Nicotine's salutary effects in patients with neurodegenerative and mental disorders have been studied a lot and are fairly well known.
Mitochondrial vacuolation may contribute to several non-apopototic cell death pathways, but its role in a wide spectrum of neurodegenerative diseases remains to be defined [ 83 84 ] .
Long polyglutamine repeats have been found in a number of transcription factors [ 39 ] . Notably, the C-terminus of murine HMG-box protein SRY contains a large polyglutamine repeat region that is responsible for the sex-determining function of this protein [ 40 ] . However, a number of neurodegenerative disorders, such as Huntington disease and spinobulbar muscular atrophy, are also strongly associated with proteins containing a polyglutamine stretch [ 41 ] . Conformational change and protein misfolding in the expanded polyglutamine region is believed to be the molecular basis of the pathogenesis [ 42 ] . Whether the presence of polyglutamine repeats in the C-terminus of human TNRC9 is important for function or alternatively hinders its ability to form a functional protein remains to be determined.