Words similar to neurodegenerative
Example sentences for: neurodegenerative
How can you use “neurodegenerative” in a sentence? Here are some example sentences to help you improve your vocabulary:
As CALB plays an important role in regulating intraneuronal cellular calcium, which protects against neurodegenerative disease and defends against apoptosis [ 48 49 50 51 52 ] , a decrease in frontal cortex CALB may result in cognitive impairment due to cell death or abnormal calcium homeostasis [ 48 49 50 51 52 ] . Furthermore, frontal cortical COX-2 was shown to significantly increase in males fed the Phyto-600 diet.
Mitochondrial vacuolation may contribute to several non-apopototic cell death pathways, but its role in a wide spectrum of neurodegenerative diseases remains to be defined [ 83 84 ] .
However, there are many case reports describing patients with progressive neurodegenerative disorders of unknown etiology, collectively referred to as neuronal intranuclear inclusion disease [ 77 ] . While these may consist mainly of unidentified poly-Gln or poly-Ala disorders, the present study raises the possibility that some forms of this disease may arise through unexpected mechanisms, perhaps involving mutations in Rab24 or other poorly characterized members of the Rab GTPase family that mediate trafficking of misfolded proteins within autophagosomes and lysosomes.
High LH levels in aging individuals may also participate in the development of inflammation-mediated neurodegenerative diseases, including Alzheimer's disease.
LHR immunoreactivity in porcine fallopian tubes was confined to the epithelium and smooth muscle cells, and in vitro LH treatment caused relaxation of the oviduct [ 35 ] . Also, LHR stimulation plays a role in the induction and maintenance of myometrial quiescence [ 36 37 38 ] . Since smooth muscles belong among important compartments of the pelvic floor, high LH levels after menopause might be involved in the increased incidence of pelvic floor disorders, a common condition in postmenopausal women [ 39 ] . Since the brain was reported to express functional LHR [ 29 30 ] , there is also a possibility that high LH levels in aging individuals may in some way participate in the development and progression of neurodegenerative process of several degenerative neurological diseases, including Alzheimer's disease.