Example sentences for: neovascularization

How can you use “neovascularization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The peripheral cornea was often thinner than normal with neovascularization.

  • Interestingly Ang-2 acts as an agonist for Tie2 receptors expressed on fibroblasts [ 6 ] . Since the neovascularization process is dependent on the dominance of angiogenic mediators over inhibitors, the higher Ang-1 mRNA and protein expression compared to Ang-2 in RA synovial tissue is of importance.

  • It has been shown that increasing amounts of Ang-2 can block the chemotactic activity of Ang-1 in endothelial cells [ 21 ] . Ang-2 alone did not stimulate corneal neovascularization, but the combination of Ang-2 and VEGF resulted in longer vessels with greater circumferential extent than those seen with VEGF alone [ 9 ] . This suggests that Ang-2 expression in the absence of VEGF leads to vessel regression, whereas expression of Ang-2 in the presence of VEGF potentiates angiogenesis.

  • Rheumatoid arthritis (RA) is characterized by synovial tissue leukocyte infiltration and angiogenesis [ 1 ] . The neovascularization process in RA is dependent on the balance between angiogenic mediators and inhibitors.

  • The regulation of MMPs by inflammatory cytokines, and the expression of MMP-9 in macrophages and vascular structures have previously suggested that MMP-9 may be associated with the synovial inflammation and neovascularization [ 35, 36].


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