Words similar to neoepidermis

Example sentences for: neoepidermis

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However, since SPARC is a matricellular protein involved in cell-matrix interaction [ 3 4 23 ] , cell-matrix interaction-related defects may exert a significant influence in large wounds of SPARC-null mice causing premature loss of a part of the scabs and of the neoepidermis, a pathophysiological process requiring repeated healing.
At day 6, reepithelialization and granulation tissue formation appeared as elaborate in SPARC-null mice as in wild-type mice with the neoepidermis and granulation tissue filling two third of the wound beds (not shown).
In large wounds (25 mm), visual examination of wounds showed that loss of wound scabs and restoration of epidermal covering were delayed in SPARC-null mice due to premature, partial loss of scabs and neoepidermis, resulting in repeated setbacks in the reepithelialization process.
Once the wound is filled with granulation tissue and covered with a neoepidermis, a portion of the wound fibroblasts transforms into myofibroblasts, which contract the wound to reduce and strengthen the defect.
Cytokeratin 14 expression is associated with proliferative epidermal keratinocytes at wound sites [ 24 ] . Such expression in control unwounded skin (0 day) is, as expected, very low but increased appreciably by day 2 after wounding with peak expression at day 4. Interestingly, expression of cytokeratin 14 was up-regulated in the normal epidermis and neoepidermis of SPARC-null mice relative to those of wild-type mice (Fig.