Example sentences for: necessitating

How can you use “necessitating” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Such divided results are typical of single-gene analyses because of limited information (~400 amino acids), necessitating combined analysis.

  • For the four rats designated for study at 6 weeks after fracture, two were lost due to the intramedullary pin backing out, necessitating early euthanasia, and one was infected and therefore unusable.

  • The anti-inflammatory activity of SSZ is due to the 5-aminosalicylic acid component while the majority of the adverse side effects have been attributed to the sulfapyridine moiety [ 14 15 16 ] . Fever, abdominal pain, and rash may develop in 3% to 20% of treated patients, but these side effects are usually mild and improve with dose reduction [ 7 11 12 ] . Severe side effects necessitating SSZ discontinuation occur in less than 5% of treated patients [ 11 ] .

  • The evidence requiring this gate is that SAR elicited by DC3000• avrRpt2 was prevented by either a npr1 mutation [ 9 ] or a ndr1 mutation [ 4 ] . We conclude that the characteristic avrRpt2 -elicited "slow HR" can only contribute to SAR in combination with NPR1 -dependent, early SA-elicited signaling, necessitating the "and" gate.

  • The authors concluded that there was substantial experimental variability in the experimental procedure, necessitating extensive filtering and large numbers of arrays to detect accurate gene expression changes (LUT: look-up tables) [ 20 ] . In our laboratory, we have processed over 1,200 Affymetrix arrays, and have found significantly higher experimental reproducibility (R 2= 0.979 for new generation U74A version 2 murine arrays or human U95 series, see Result and Discussion).


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