Words similar to necessary

Example sentences for: necessary

How can you use “necessary” in a sentence? Here are some example sentences to help you improve your vocabulary:

Biochemical studies of Btk-deficient B cells have shown Btk to be necessary for BCR-induced phospholipase C-γ2 (PLCγ2) phosphorylation, calcium mobilization, extracellular signal-regulated kinase (ERK) and c-Jun NH 2 -terminal kinase (JNK) mitogen-activated protein kinase (MAPK) activation, NF-κB activation and apoptosis [ 7, 8, 9, 10, 11, 12].
To determine whether SKP2 downregulation is a necessary step in MIB-induced p27 upregulation, LNCaP cells were blocked with MIB for 72 h, followed by infection with Ad-SKP2 or Ad-SKP2-ΔF for various periods.
Basolateral HCO 3 -cotransport is necessary for proper buffering of digestive enzymes secreted by the pancreas [ 4].
Pointing out that Netanyahu had battled against the Oslo accords and promised his fellow countrymen that they wouldn't have to give up territory in exchange for peace, Le Monde said he has now come to recognize that territorial concessions are necessary.
Thus, neither Genie nor GENSCAN correctly predicted the structure of these two genes; each correctly predicted aspects of the gene models, but EST and BLASTX data were necessary to accurately determine the structure of the two genes.