Example sentences for: nadph

How can you use “nadph” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Secondly, disruption of normal lysosomal pH by lysosomotropic weak bases inhibits the respiratory burst in neutrophils [ 12 ] . A normal transmembrane pH gradient in lysosomes is suggested to play an important role in assembling the NADPH oxidase complex during cell activation.

  • The PGM activity assay is indirect and is coupled to the conversion of NADP +to NADPH.

  • Although the location of activated NADPH oxidase complex in phagolysosomes has been reported, the release of either H 2 O 2 or O 2 •- in situ upon stimulation with PMA has not been directly shown in live cells [ 10 11 ] . In order to directly measure the oxidative activity in lysosomes, I use a reduced fluorescein derivative that is conjugated with BSA, OxyBURST Green H 2 HFF BSA, as shown in Figure 1. Spectrofluorimetric analysis indicates that this reduced compound is non-fluorescent, and becomes fluorescent upon HRP-catalyzed oxidation.

  • First, it has been shown that activation of NADPH oxidase during a phagocytosis event results in alkalization of phagolysosomal pH in the human neutrophil [ 10 ] . The phagolysosomal pH is influenced by NADPH oxidase activity and to a lesser extent by a Na +/H +antiporter.

  • contains three glutaredoxins that utilize the reducing power of glutathione to catalyze the reduction of disulfide bonds (–S–S–) in the presence of NADPH and glutathione reductase.


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