Words similar to myeloma
Example sentences for: myeloma
How can you use “myeloma” in a sentence? Here are some example sentences to help you improve your vocabulary:
As mentioned above, IL-6 is a cytokine that functions as a necessary growth factor in several cancer types, most studied in multiple myeloma [ 12 ] . It is an essential factor in the development and maintenance of B cell neoplasms [ 13 ] , and likely plays an important role in many other types of cancer.
Titrated concentrations of IgG 1 and IgG 2a myeloma proteins were used to generate a standard curve, and the IgGs were detected with the same labeled rabbit anti-mouse IgG 1 or IgG 2a antiserum.
Although other conditions such as head injury [ 38, 39, 40], Paget's disease [ 41, 42, 43], arteriovenous fistula [ 44], severe anemia [ 45, 46], multiple myeloma [ 47], thyrotoxicosis [ 48], and spinal cord injury [ 49] have been reported to produce a low SVR, this patient lacked any clinical evidence suggesting one of these diagnoses; his hypotension resolved spontaneously.
Experimental anti-IL-6 therapies for myeloma and B-lymphoproliferative disorders have been shown to be of some use in limited clinical trials [ 6 7 8 9 10 11 ] , therefore this is an intensely-studied target for myeloma therapy.
For example, early investigators observed that transfection of untransformed B cells with a plasmid for constitutive expression of IL-6 conferred the tumorigenic phenotype on the cells [ 2 ] . IL-6 is a key factor in myeloma progression and survival [ 3 4 ] , and also in Kaposi's sarcoma, a solid tumor [ 5 ] . In myeloma, the standard therapy for treatment includes prednisone, which acts by inhibiting IL-6 synthesis.
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